Protein Alignment CG42269 and SVOP

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_061181.1
• Gene: SVOP / 55530
• HGNCID: 25417
• Length: 548
• Species: Homo sapiens
• Alignment Length: 610
• Identity: 143/610 - (23%)
• Similarity: 228/610 - (37%)
• Gaps: 139/610 - (22%)

  Fly    28 GADALHRRKSGGGNKELQLDMGGFKKGQEMAGGNGSDSLP-----PSMD---FDDILPLIGEFGR 84
            |..|.....:..|..|:|::  |...|.|....:...::|     |:.|   .:|.:..|| ||:
Human    20 GESARSEDDTASGEHEVQIE--GVHVGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIG-FGK 81

  Fly    85 YQKLLFICMIPFSFFVAFVYFSQIFLTLIPEQHWCHVPELDGLDVEARLALSIPMTNGEYNNCYM 149
            :|..|.:                                |.||                   .:|
Human    82 FQWKLSV--------------------------------LTGL-------------------AWM 95

  Fly   150 YDVNYTDILAQGKVMADPKWPQVKCRHGWSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLG 214
            .|.....||:   ::|    ||:.|.  |     .:|        :|   ..||.|   |:.|:|
Human    96 ADAMEMMILS---ILA----PQLHCE--W-----RLP--------SW---QVALLT---SVVFVG 132

  Fly   215 AIVGGLLFGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYIL 279
            .:....|:|.::|::||...|..:.:..|..|:.:||...:....::|..|||.... ......|
Human   133 MMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGG-VPQSVTL 196

  Fly   280 VLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFL---ADWKLLAIVTSAPLLLAIFTPFVVPE 341
            ..|::..|.|. ...:.|.:|:.........:|.|:   ..|:.|.|:::.||||.....|.:||
Human   197 YAEFLPMKARA-KCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPE 260

  Fly   342 SARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRL 406
            |||:.|..|..:||:..||::...||..:|         ..|.:..::...||  :.||| :|..
Human   261 SARYDVLSGNQEKAIATLKRIATENGAPMP---------LGKLIISRQEDRGK--MRDLF-TPHF 313

  Fly   407 RRTTLLLIVIW------------MAISLVFDGHVRNVGSLGLDIFFTFTLAC------------- 446
            |.|||||..||            :...|...|.|..:.|....:....:|||
Human   314 RWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCGISSRKKAVEAKCSLACEYLSEEDYMDLLW 378

  Fly   447 --FTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGIYSAALAIMGRFFVNISYNI 509
              .:|.|...:...|:||.||:.......|:....|||..:.........|..:.|.|::..:..
Human   379 TTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFIARAFISGGFQA 443

  Fly   510 GLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVV-YLANISQALPLIILGILGIIGGLLALLL 573
            ...:..||.||..||..:.....|..|.::|.||:. .:...|..|.|.:.....::..|.:..|
Human   444 AYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFL 508

  Fly   574 P-ETLNHVLPQTLSD--GEEF-GRG 594
            | ||....|.::...  |:|. |||
Human   509 PIETKGRGLQESSHREWGQEMVGRG 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	116/502 (23%)
		MFS	206..545	CDD:119392	94/368 (26%)
SVOP	NP_061181.1	MFS_SVOP	87..509	CDD:340999	115/514 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910