Protein Alignment CG42269 and SLC22A15

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_060890.2
• Gene: SLC22A15 / 55356
• HGNCID: 20301
• Length: 547
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 160/591 - (27%)
• Similarity: 271/591 - (45%)
• Gaps: 89/591 - (15%)

  Fly    70 MDFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTLI---PEQHWCHVPELDGLDVEA 131
            |:.::....:||.|.||  :::|.:.......:|....|.:.|:   |..||
Human     1 MEVEEAFQAVGEMGIYQ--MYLCFLLAVLLQLYVATEAILIALVGATPSYHW------------- 50

  Fly   132 RLALSIPMTNGEYNNCYMYDVNYTDILAQGKVMADPKW------PQVKCRHGWSYNFTEIPYATV 190
            .||..:|  |..:.|           .:.|:..|...|      .::.....:|.:||     ::
Human    51 DLAELLP--NQSHGN-----------QSAGEDQAFGDWLLTANGSEIHKHVHFSSSFT-----SI 97

  Fly   191 ATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNF 255
            |:|...:.:.:...:.|.|.||.|..||.:.||.::|||||....:....:.:|..:...|..::
Human    98 ASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSY 162

  Fly   256 WEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFLADWKL 320
            ..||:.||.||........:.::|:.|.||..|.....::. .:||.........:.||:..|:.
Human   163 EFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIAQYALLGYFIRSWRT 226

  Fly   321 LAIVT----SAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQI---F 378
            |||:.    :...||::|    :|||.|||.|||::.:|...|..:.|.|.:.  ..|:.:   .
Human   227 LAILVNLQGTVVFLLSLF----IPESPRWLYSQGRLSEAEEALYLIAKRNRKL--KCTFSLTHPA 285

  Fly   379 TDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGSLGLDIFFTFT 443
            ..||:       :.|  |.||||:...|...||:|:.||...|||:.|...:.|.||..|:....
Human   286 NRSCR-------ETG--SFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLA 341

  Fly   444 LACFTELPADTLLTVILDR--FGRRWLACSSMVLSGVFSLLATVVP----VGIY----SAALAIM 498
            |:...|:|:..|...::::  |||:....:.:.|.|:..|:...:|    .|::    |.:|:::
Human   342 LSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLL 406

  Fly   499 GRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIILGILG 563
            |:..::.::||...:.:|:.|||:|...:....:...|..|||||:..|..:..:||.|:.|..|
Human   407 GKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATG 471

  Fly   564 IIGGLLALLLPETLNHVLPQTLSD---------GEEFGRGQSIWDFPCLAKQ-----VDDDEDEK 614
            :..|||:||||||||..|.:|.||         |||....|::....|:.|:     ..::|:|.
Human   472 LTSGLLSLLLPETLNSPLLETFSDLQVYSYRRLGEEALSLQALDPQQCVDKESSLGSESEEEEEF 536

  Fly   615 RNADVE 620
            .:||.|
Human   537 YDADEE 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	128/497 (26%)
		MFS	206..545	CDD:119392	102/355 (29%)
SLC22A15	NP_060890.2	MFS	111..469	CDD:119392	106/373 (28%)
		MFS_1	111..450	CDD:284993	99/354 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547		6/21 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153629
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850