DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42269 and Orct2

DIOPT Version :9

Sequence 1:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster

Alignment Length:	595	Identity:	187/595 - (31%)
Similarity:	307/595 - (51%)	Gaps:	57/595 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 MDFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTLIPEQHWCHVPELDG--LDVEAR 132
            |.:|:.:..:|:||||||:::..:...|..|||...:.:||...|:.. |.:|..:|  .|:...
  Fly     1 MGYDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFR-CALPFENGSSYDLPTH 64

  Fly   133 L-ALSIPMTNGEYNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGWSYNFTEIPYATVA-TEQN 195
            | .||.|    |...|..|||:||:....|.:.......:. |.   ||.:....|...| ||.|
  Fly    65 LWNLSYP----ENERCSYYDVDYTEEYLNGSIPRSSNETKT-CS---SYVYDRSKYLNSAVTEWN 121

  Fly   196 WVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNFWEFAI 260
            .||....:...:.|:|.||.::|.::||.::|::||.|.|..:.::.:|.||.......::.:..
  Fly   122 LVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTF 186

  Fly   261 MRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFLADWKLLAIVT 325
            .|..||......|.:.|::.:|.|||..|.: |.:.:.:||:....|....|||:.||:.|.|..
  Fly   187 ARLMVGATTSGVFLVAYVVAMEMVGPDKRLY-AGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIAL 250

  Fly   326 SAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTD--------SC 382
            :.|.|:.:|..:::|||||||:.:|:.|.|:..::|..:.|..::..:......|        :.
  Fly   251 TLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAK 315

  Fly   383 KRMQEQEAQNG-KYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGSLGLDIFFTFTLAC 446
            :::::||...| ..||.|||..|.|||.|||:.:.|:..|.|:.|...|..:||.::...|.::.
  Fly   316 QKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISG 380

  Fly   447 FTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATV-VPVGIYS--AALAIMGRFFVNISYN 508
            ..|:||...|.:.|:|:|||.:.|..:|::|: |||||| :|..:::  .|.|::|:..:..||.
  Fly   381 AVEIPAYIFLLLTLNRWGRRSILCGCLVMAGL-SLLATVIIPQRMHTLIVACAMLGKLAITASYG 444

  Fly   509 IGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIILGILGIIGGLLALLL 573
            ....::||..|||||..|:....::..::.::|||:.:||.|.:.|||:|.|.|.::.|||:|||
  Fly   445 TVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLLSLLL 509

  Fly   574 PETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDDDEDEKRNADVEEVRSQAFVRGTQTGASLN 638
            |||.|..:.:|::|||.||:                    |..|||.          .:||..|.
  Fly   510 PETHNKPMLETIADGERFGK--------------------KTKADVY----------LETGQELR 544

  Fly   639 ASTGGELRSS 648
            |.....|:.|
  Fly   545 APEAQPLKGS 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	153/487 (31%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	110/350 (31%)
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	169/519 (33%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	119/377 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458399
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3B9N9
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.890