DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42269 and CG17751

DIOPT Version :9

Sequence 1:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	548	Identity:	176/548 - (32%)
Similarity:	289/548 - (52%)	Gaps:	46/548 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 MDFDDILPLIGEFGRYQKLLFICMIPFSFFVAFV-YFSQIFLTLIPEQHWCHVPELDGLDVEARL 133
            ||...:|...|.||.|| :|.:.:..::..|:.: ||||..::..| .|.|..||
  Fly     1 MDLQSVLEKCGNFGPYQ-ILLLGLFGYTNIVSSLHYFSQTIISFTP-SHRCSRPE---------- 53

  Fly   134 ALSIPMTNGEYNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGWSYNFTEIPYATVATEQNWVC 198
                           .|..|.|.:|:...:..|.::   ||. .|.:. .|..|.::.||..|||
  Fly    54 ---------------DYQPNSTSLLSCSVMQFDKEF---KCT-SWDFE-RESNYESITTELEWVC 98

  Fly   199 DDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNFWEFAIMRF 263
            |||......||.||:|:.:|.:.||::|||.||:||.:.:.:.|......|:||.:...|:..||
  Fly    99 DDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRF 163

  Fly   264 FVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFLADWKLLAIVTSAP 328
            ..|...|..:.:|||||.||:.|::|||..|:.:.:|:.....:.||||.::.:|:......|.|
  Fly   164 ISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLP 228

  Fly   329 LLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCKRMQEQEAQNG 393
            .|..:..|..:.|||.||:::||.:||...|:.:.|.|||||....:..|....:..........
  Fly   229 ALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNSQNKS 293

  Fly   394 KYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGSLGLDIFFTFTLACFTELPADTLLTV 458
            ..:.:.:.::||||:.|::|::..|.|::.||...|||..:|:..|..|:.:.|..|||.  ||:
  Fly   294 SDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAG--LTI 356

  Fly   459 IL--DRFGRRWLACSSMVLSGVFS-----LLATVVPVGIYSAALAIM---GRFFVNISYNIGLQW 513
            ||  ::.||:.:||:|:.:..:.:     |:||:.| ..||..|..|   ||:...::|:...|:
  Fly   357 ILFQNKIGRKGMACASLFVGAIITAATGYLVATLDP-SDYSVLLGFMVSLGRYGAVVAYDAEAQY 420

  Fly   514 AAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIILGILGIIGGLLALLLPETLN 578
            |||::||.|:.:.||.||::|...:..:.:::||....:.||.:::..:.:||..|.|.|||||:
  Fly   421 AAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETLH 485

  Fly   579 HVLPQTLSDGEEFGRGQSIWDFPCLAKQ 606
            ..|||.|.:||.|.:|:..:.|||.:::
  Fly   486 KNLPQNLEEGEMFAKGEKWYFFPCFSRR 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	151/482 (31%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	115/348 (33%)
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	163/513 (32%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	122/374 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.960