Protein Alignment CG42269 and Slc22a20

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_941052.1
• Gene: Slc22a20 / 381203
• MGIID: 2685809
• Length: 556
• Species: Mus musculus
• Alignment Length: 592
• Identity: 158/592 - (26%)
• Similarity: 266/592 - (44%)
• Gaps: 67/592 - (11%)

  Fly    70 MDFDDILPLIGEFGRYQKLLF--ICMIPFSFFVAFVYFSQIFLTLIPEQHWCHVP--------EL 124
            |.|.|:|..:|..||:| |::  :.::|........ |.|.|....|..| |..|        .:
Mouse     1 MAFTDLLDALGGVGRFQ-LVYTALLLLPCGLLACHT-FLQNFTAAAPPHH-CQHPANYTEPTTNV 62

  Fly   125 DGLDVEARLALSIPMTNGEYNNCYMYDVNYTDILAQGKVMADPKWPQVK------------CRHG 177
            .|:.:.|.:.|:   .:|:...|..|              .:|:|..:|            |:.|
Mouse    63 SGVWLRAAIPLN---QHGDPEPCRRY--------------VEPQWALLKPNASSHGVATEGCKDG 110

  Fly   178 WSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMG 242
            |.|:.:..| :|:..|.:.||:...|...||||:..|.:||..|||.:|||.||...|:.:.:..
Mouse   111 WVYDRSIFP-STIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQL 174

  Fly   243 LLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACL 307
            .::|..||:|.:|..:.:.||.:|..|.........||:|::..:.|| ||.:.:...||....:
Mouse   175 AVSGAATAYVGSFSAYCVFRFLMGMTFSGIILNSLSLVVEWMPTRGRT-VAGILLGFSFTLGQLI 238

  Fly   308 LPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPP 372
            |..:||.:..|:.|....|||.|:.....:.:|||:|||:..||..:||..|:|:...|||:...
Mouse   239 LAGVAYLIRPWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEG 303

  Fly   373 QTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGSLGLD 437
            :.......|.....|..:.....|:||||::|.:||.|..|:.:|.:.|:.:.|...::...||.
Mouse   304 ERLTTEVVSSYIQDEFASVRTSNSILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLS 368

  Fly   438 IFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGIYS--AALAIMGR 500
            |:....|....::||..:.|..:...|||....|.::|:|:..:....:|..:.:  ...|.:|:
Mouse   369 IYLVQALFGIIDIPAMLVATTTMIYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGK 433

  Fly   501 FFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIILGILGII 565
            ..:..|:.....:..|:.||.:|...:.|..:...:..::||.:..|..||..||.:..|...::
Mouse   434 GCLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVL 498

  Fly   566 GGL-LALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDDDEDEKRNADVEEVRSQAFVR 629
            .|: :|..|.||.|..|.:|::..|.            ..||.....|.::.:  ||:..|
Mouse   499 AGMAVACFLTETRNVPLVETIAAMER------------RVKQGRSKRDTEQKS--EEISLQ---- 545

  Fly   630 GTQTGAS 636
              |.|||
Mouse   546 --QLGAS 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	131/495 (26%)
		MFS	206..545	CDD:119392	97/340 (29%)
Slc22a20	NP_941052.1	2A0119	11..518	CDD:273328	142/528 (27%)
		MFS	138..507	CDD:119392	105/369 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..556		10/33 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.950