DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42269 and SPAPB1E7.08c

DIOPT Version :9

Sequence 1:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_594134.1	Gene:	SPAPB1E7.08c / 2543660	PomBaseID:	SPAPB1E7.08c	Length:	554	Species:	Schizosaccharomyces pombe

Alignment Length:	600	Identity:	125/600 - (20%)
Similarity:	207/600 - (34%)	Gaps:	189/600 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 DSLPPSMDF-----------DDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFS--------QIF 109
            |.|..|.||           .:.:..|| |||||..||       |...|.:.|        .:.
pombe    46 DDLFDSNDFSKTYLAKSRILSNAMNEIG-FGRYQWYLF-------FVAGFGWMSDNIWPVCTSLI 102

  Fly   110 LTLIPEQHWCHVPELDGLDVEARLALSIPMTNGEYNNCYMYDVNYTDILAQGKVMADPKWPQVKC 174
            |..:.|....|.|                                    |:|:.
pombe   103 LMRLDEVDGPHPP------------------------------------AEGRA----------- 120

  Fly   175 RHGWSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPA----L 235
                       ||.|::  ||                 ||.:||.:::...||..||..|    .
pombe   121 -----------PYLTLS--QN-----------------LGLLVGAMVWSLSADTIGRRWAFNLTF 155

  Fly   236 IGTNMMGLLAGVGTAFVSNFWEFAIMRFFVG--FAFDNCFTMMYILVLEYVGPKYRTFVANMSIA 298
            :.|.:..::||....|.|.....|:..|.||  ...|:.      :.||.:...::..:..||
pombe   156 LFTGVFAVIAGASPNFASICVFDALWSFGVGGNLPVDSA------IFLEALPSSHQWLLTVMS-- 212

  Fly   299 IFFTGA-----ACLLPW--IAYF----------LAD---WKLLAIVTSAPLLLAIFTPFVVP--E 341
              |..|     |.|:.|  |:.|          .||   |:..........||.....|:|.  |
pombe   213 --FWWAIGQVIANLVSWGLISNFSCPDDESVCHRADNKGWRYFLFTMGGMTLLMFAARFLVSVYE 275

  Fly   342 SARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCKRMQEQEAQNGKYS---------- 396
            |.::.:::|...|||..:.|:.:.||:.......:::....:..:|.:..:.|.|
pombe   276 SPKFYLAKGDDYKAVETIHKIARINGKTCTLTVEELYAIDRQEQEESDLDDSKSSDAKSVTQGTT 340

  Fly   397 --------------VLDLFKSPRLRRTTLLLIVIWMAISLVFDGH---------VRNVGSLGLDI 438
                          :...|.|.:|..:::|:|:.|..|.|.|..:         .|...:..|.:
pombe   341 NLIVEKLRKYNFEHIRQCFGSRKLAISSILVILSWAVIGLAFPLYNAFLPYYLETRGNANEPLSV 405

  Fly   439 FFTFTLACFTE---LPADTLLTVILD-RFGRRWLACSSMVLSGVFSLLATVVPVGIYSAALAIMG 499
            ..|:..:....   :|...:..|::: |.||:...|.|::|:|||...:|..     ..:.|.:|
pombe   406 AKTYRNSLIVSAIGVPGSLIAGVLVEFRIGRKGTLCLSLILTGVFLFASTTA-----KTSNAYLG 465

  Fly   500 -----RFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIIL 559
                 .||.:|.|.:...:..||.|:.||..||........:..|.:|.:...||::.:.|:.:.
pombe   466 WNCTFSFFSDIMYGVLYAYTPEVFPSKVRGTAVGLAASANRILGIFSPVIAMRANLTTSAPIFVS 530

  Fly   560 GILGIIGGLLALLLP 574
            |.|.|..|:|.:..|
pombe   531 GALFIFAGILVVFFP 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	112/549 (20%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	88/408 (22%)
SPAPB1E7.08c	NP_594134.1	2A0109	68..552	CDD:129965	119/577 (21%)
SPAPB1E7.08c	NP_594134.1	MFS	122..545	CDD:119392	100/456 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I2349
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050