Protein Alignment CG42269 and Slc22a15

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001034460.2
• Gene: Slc22a15 / 242126
• MGIID: 3607704
• Length: 544
• Species: Mus musculus
• Alignment Length: 588
• Identity: 159/588 - (27%)
• Similarity: 261/588 - (44%)
• Gaps: 86/588 - (14%)

  Fly    70 MDFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTLI---PEQHWCHVPELDGLDVEA 131
            |:.::....:||.|.||  :::|.:.......:|....|.:.||   |..||      |..|:
Mouse     1 MEVEEAFQAVGEMGLYQ--MYLCFLLAVLLQLYVATEAILIALIGATPAYHW------DMADL-- 55

  Fly   132 RLALSIPMTNGEYNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGW--SYNFTEI--------P 186
                   :.|..::|         ..|.:|:...|           |  :.|.:||        .
Mouse    56 -------LPNQSHSN---------QTLGKGQAFGD-----------WLLTANGSEIHKHVHFSNS 93

  Fly   187 YATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGLLAGVGTAF 251
            :.::|:|...:.:.:...:.|.|.||.|..||.:.||.::|||||....:....:.:|..|...|
Mouse    94 FTSIASEWFLIANRSYKVSAASSSFFSGVFVGVISFGQLSDRFGRRKVYLTGFALDILFAVANGF 158

  Fly   252 VSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFLA 316
            ..::..||:.||.||........:.::|:.|.||..|.....::. .:||.........:.||:.
Mouse   159 SPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIAQYALLGYFIR 222

  Fly   317 DWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDS 381
            .|:.||::.:....|.......:|||.|||.|||::.:|...|..:.|.|.:.           .
Mouse   223 SWRTLAVLVNLQGTLVFLLSLFIPESPRWLYSQGRLSEAEEALYFIAKRNRKL-----------K 276

  Fly   382 CKRMQEQEAQNGKY----SVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGSLGLDIFFTF 442
            |.......| |..|    |.||||:...|...||:|:.||...|||:.|...:.|.||..|:...
Mouse   277 CTFSLTHPA-NRSYRATGSFLDLFRYRILLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANL 340

  Fly   443 TLACFTELPADTLLTVILDR--FGRRWLACSSMVLSGVFSLLATVVP----VGIY----SAALAI 497
            .|:...|:|:..|...::::  |||:....:.:.|.|:..|:...:|    .|::    |.:|::
Mouse   341 ALSGLIEIPSYPLCIYLINQRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSL 405

  Fly   498 MGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIILGIL 562
            :|:..::.::||...:.:|:.|||:|...:....:...|..||||||..|..:..:||.|:.|..
Mouse   406 LGKLTISAAFNIVYIYTSELYPTVIRNVGLGACSMFSRVGGIIAPFVPSLKEVQWSLPFIVFGAT 470

  Fly   563 GIIGGLLALLLPETLNHVLPQTLSD---------GEEFGRGQSIWDFPCLAKQVDDDEDEKRNAD 618
            |:..|||:||||||||..|.:|.||         |||....|::.....|.|...:.|:|:...|
Mouse   471 GLTSGLLSLLLPETLNSPLLETFSDLQMYSYRRLGEEALSLQTLDPPQPLDKVSSESEEEEEFYD 535

  Fly   619 VEE 621
            .:|
Mouse   536 ADE 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	128/498 (26%)
		MFS	206..545	CDD:119392	100/352 (28%)
Slc22a15	NP_001034460.2	MFS	121..469	CDD:119392	101/360 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..544		6/26 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843806
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850