Protein Alignment CG42269 and Slc22a22

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_036015188.1
• Gene: Slc22a22 / 210463
• MGIID: 2446114
• Length: 587
• Species: Mus musculus
• Alignment Length: 637
• Identity: 157/637 - (24%)
• Similarity: 267/637 - (41%)
• Gaps: 125/637 - (19%)

  Fly    70 MDFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVY----FSQIFLTLIPEQHWCHVPELD----- 125
            ||||:||..:|:.||:|    ||||.....::.|.    ..:.|...||..| |.: .||
Mouse     1 MDFDEILHHVGDSGRFQ----ICMIILLNILSLVLSPHDVLENFTAAIPAHH-CSI-NLDNSRSE 59

  Fly   126 -----GLDVEARLALSIPMTNGE---------YNNCYMYDVNYTDILAQGKVMADPKWPQVKCRH 176
                 .|..|..:.:||||...:         |......|.|.:...:. ::..:|      |..
Mouse    60 VSTDMNLTTEDLMKVSIPMGPNQKPEQCRRFRYTQWQFLDSNISTFNST-ELETEP------CLD 117

  Fly   177 GWSYN---FTEIPYATVATE-----QNW----------------------------VCDDAALPT 205
            ||:|:   ||    :|:.||     |.|                            |||..:...
Mouse   118 GWTYDHSVFT----STIVTEGLSPPQPWDSDQYYHTKHEISPCEEGLKSSVKVWDLVCDFQSFKY 178

  Fly   206 YAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFD 270
            |||:....|.:|...|.|.::|||||.|.|:..::.....|...||..||..:.::||.:. ||.
Mouse   179 YAQATSLAGHLVSCPLSGIISDRFGRKPLLMYCSLAYGAVGTYCAFAPNFSVYCVLRFLLS-AFQ 242

  Fly   271 NCFTM-MYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFLADWKLLAIVTSAPLLLAIF 334
            :...: ..|||||....::...:..:| .:|.:....:|..:||.::||.||.:..:.|..: .|
Mouse   243 STILINSLILVLEEASVQWHPTIIVLS-GLFNSIGQGVLGGLAYVISDWHLLQLAYALPFFI-FF 305

  Fly   335 TPFV-VPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCK-RMQEQEAQNGK-YS 396
            ..|. ||||.|||:..||.|:|...|:::...||::...|  .:.|:..: ::::.....|| :.
Mouse   306 VLFCWVPESVRWLIITGKTDQAWKELQRIASINGKKGIAQ--NLTTEDLRSKLKKDVNSTGKLFR 368

  Fly   397 VLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGSLGLDIFFTFTLACFTELPADTLLTVILD 461
            :.|:|.:|.:|:..|....:..|....|.|.:.:|..||.::|.|.......::|:.:|....:.
Mouse   369 IKDIFINPLIRKIVLSNSSLLFAELFSFVGLLLDVQLLGKNMFLTQIFLGAIDVPSKSLTYFTIR 433

  Fly   462 RFGRRWLACSSMVLSGVFSLLATVVPVGIY--SAALAIMGRFFVNISYNIGLQWAAEVLPTVVRA 524
            ...||.|....::.:|....:...:...:|  ...:.|:|:........|...:..|:.|..:|:
Mouse   434 NVSRRPLIAFLLLTTGSCITITIFISEEMYVLRTIIFILGKGCFAAFTCISTTYINELSPVELRS 498

  Fly   525 QA----VAFIHIMGYVASI---IAPFVVYLANISQALPLIILGILGIIGGLLALLLPETLNHVLP 582
            ..    :|.:.:.|.::::   ...:.||       ||:|:.|:|.|:..:..|.||||.|  ||
Mouse   499 TLNGVFLAVVRLAGVLSALTLATRKYFVY-------LPMILYGVLPIVATISILFLPETFN--LP 554

  Fly   583 QTLSDGEEFGRGQSIWDFPCLAKQVDDDEDEKR--NADVEEVRSQAFVRGTQ 632
            .|              |.      :.|.|..||  :.::.:...|.|:..|:
Mouse   555 HT--------------DI------IKDMEKRKRLMSKNISKKEGQDFLETTE 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	128/543 (24%)
		MFS	206..545	CDD:119392	86/351 (25%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	110/462 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844064
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940