Protein Alignment CG42269 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 571
• Identity: 153/571 - (26%)
• Similarity: 263/571 - (46%)
• Gaps: 60/571 - (10%)

  Fly    70 MDFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTLIPEQHWCHVPELDG-------- 126
            |.|.::|..:|..||:|....:.::....:|......:.|...:| .|.|.||.||.
Mouse     1 MAFPELLDRVGGLGRFQLFQTVALVTPILWVTTQNMLENFSAAVP-HHRCWVPLLDNSTSQASIP 64

  Fly   127 --LDVEARLALSIPM-TNGEYNNCYMYDVNYTDILAQGKVMADPKWPQVK--------------- 173
              |..:..||:|||. .:.:.:.|..:              ..|:|...:
Mouse    65 GDLGPDVLLAVSIPPGPDQQPHQCLRF--------------RQPQWQLTESNATATNWSDAATEP 115

  Fly   174 CRHGWSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGT 238
            |..||.|:.:.. .:|:.|..:.||:..||...|||||..|.:||..:.|..:|||||...|..:
Mouse   116 CEDGWVYDHSTF-RSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWS 179

  Fly   239 NMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTG 303
            .::..::|...||:..|..:.:.||.:..|..........|::|:...:....|..:: |:.|:.
Mouse   180 YLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTLN-ALGFSF 243

  Fly   304 AACLLPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGR 368
            ...|...:||.:..|::|.:..|||..|.....:.:|||||||::.||:|:.:..|:::...|.|
Mouse   244 GQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRR 308

  Fly   369 QVPPQTYQIFTDSCKRMQEQEAQNGK--YSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNV 431
            :....|  :..:..:...|:|....|  .|:..|..:|.||..|::.::.|.|....|.|...::
Mouse   309 KAEGDT--LTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISMLCWFAFGFTFYGLALDL 371

  Fly   432 GSLGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVP--VGIYSAA 494
            .:||.:||....|....:.|..|...:::.|.|||....|.:||.|:..|...:||  :|:..:|
Mouse   372 QALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPGLCILSNILVPHGMGVLRSA 436

  Fly   495 LAIMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIIL 559
            ||::|...:..::.....:::|:.|||:|..||....:.....:::.|.|..|......:||::.
Mouse   437 LAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVY 501

  Fly   560 GILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDDD 610
            |::.::.||.|||||||.|..||.|:.|.::    ||:       |:|..|
Mouse   502 GVVPVLSGLAALLLPETKNLPLPDTIQDIQK----QSV-------KKVTHD 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	128/501 (26%)
		MFS	206..545	CDD:119392	94/342 (27%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	143/533 (27%)
		MFS	147..516	CDD:119392	104/371 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843330
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.950