DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42269 and oct-2

DIOPT Version :9

Sequence 1:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_509899.3	Gene:	oct-2 / 181325	WormBaseID:	WBGene00003843	Length:	757	Species:	Caenorhabditis elegans

Alignment Length:	620	Identity:	159/620 - (25%)
Similarity:	276/620 - (44%)	Gaps:	91/620 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 MDFDDILPLIGEFGRYQKLLFICM----IPFSFFVAFVYFSQIFLTLIPEQHWCHVPELDGLDVE 130
            :||:.||.|||....:|.::::.:    :|.:.|    ..|.:::...|: |||.:|..:.....
Worm   154 IDFEGILQLIGGCSYWQIIVYLIISVQQVPHAMF----NLSVVYMMYQPD-HWCKIPFFNEESFS 213

  Fly   131 ARL-------------ALSIPMTNGEYNN------CYMYDVNYTDILAQGKVMADPKWPQVK--- 173
            |.|             .::.|.|..:..|      |:.::.:|..|...       .|.|||
Worm   214 AELGYTNYTWDQVLNSTIAFPRTFNKQRNELHHDQCHYFERDYVHIKLS-------PWAQVKDMN 271

  Fly   174 -------CRHGWSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGR 231
                   |:. |.|: |.:...|:.||.|.|||:.....:....:.||.:||..:.|:::||:||
Worm   272 ATGKINRCKE-WEYD-TSVMDRTIVTEWNRVCDNNWSRAHVHMSYSLGYLVGCFVGGFISDRYGR 334

  Fly   232 IPALIGTNMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMS 296
            ..|:.|..::.:|.|....:...|..|.::||.:....:......|:|.:|..|.|||:.|.::.
Worm   335 KTAITGFGILTMLFGFLLTYSKEFEIFLVVRFLLAATNEAADLAAYVLCMEVTGTKYRSIVGSLI 399

  Fly   297 IAIFFTGAACLLPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKK 361
            .|.:..|.| .|..|||....|.::.::.....::::...:.:|||.|||:...|..:|..|:::
Worm   400 QAPWACGYA-FLALIAYLTKSWTMIHLICVLLHIISLMLLYFLPESPRWLILNNKTKQAEKIIRE 463

  Fly   362 LEKGNGRQVPPQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDG 426
            ....|..::|.....:.....|:..:   .|.|.|...||:|..||...::|.::|:|.:||:.|
Worm   464 ACHYNKSRLPSDLGLVRHAEKKKWMK---HNEKPSYFHLFRSSELRFRNVVLFIVWIATALVYYG 525

  Fly   427 HV---RNVGSLGL-----DIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLA 483
            .|   .:..|.|.     :.|....:|...|||. .:..|.|.|.||:......:..||:| ||.
Worm   526 MVIALSDQSSPGRRVFDGNFFLNNAMAGAIELPT-LVFCVFLLRMGRKRSQMLVLFGSGLF-LLT 588

  Fly   484 TVVPVGIYSAALA----IMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFV 544
            :||.|....:.||    ::.:..:..|:||...:.:|:.|||||..||....::..:.:..:.::
Worm   589 SVVMVYRKQSTLALIFMLLSKACIQGSFNILYIFTSELNPTVVRNSAVGISSMVARMGAGASGYI 653

  Fly   545 VYLANISQAL-PLIILGILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPC------ 602
            ..|::::..| |:.|.....::.|.|.||||||....||.|:.|..:..:..:   .||
Worm   654 AILSDVTMPLVPMTIFACFSLLAGCLVLLLPETQGLPLPDTILDSVQMVKRNT---KPCGTLSGT 715

  Fly   603 ---------------LAKQV-DDDEDEKRNADVEE 621
                           |..:| .|||:|:...|.||
Worm   716 FLGGIDDDAQPYGGKLPPRVSSDDEEEEEEEDSEE 750

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	127/516 (25%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	93/350 (27%)
oct-2	NP_509899.3	MFS_SLC22	281..673	CDD:340875	107/399 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163147
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840