DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42269 and Y82E9BR.16

DIOPT Version :9

Sequence 1:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001022960.1	Gene:	Y82E9BR.16 / 175300	WormBaseID:	WBGene00022348	Length:	575	Species:	Caenorhabditis elegans

Alignment Length:	598	Identity:	151/598 - (25%)
Similarity:	269/598 - (44%)	Gaps:	83/598 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 MDFDDIL-PLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTL-----------IPEQHWCHVP 122
            |.|||.| ..:||.|:|||:.|..:...:..|:....|..|.::           :||:...:..
Worm     1 MKFDDFLFTYLGEMGKYQKIQFFLVCLPTIVVSMHALSWTFASVDTPYRCRLPSDLPEKEPYYTT 65

  Fly   123 ELDGL----DVEARLALS---IPMTNGEYNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGWSY 180
            .|:..    |.:|.:.:|   .|.....|:.|.:.| |.|                  | |...:
Worm    66 LLNFTKCTNDADANVPISEYGKPGVTCHYDRCTLPD-NET------------------C-HEHIF 110

  Fly   181 NFTEIPYATVATEQNW--VCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGL 243
            :.:::.|..|   |.|  .||.:.:....|:.:::|.:.|...||.:.||.||........::.:
Worm   111 DHSKVEYTAV---QRWEITCDRSWIKATIQAAYYVGQMAGSTTFGMLGDRIGRKKVFFLAIVIQI 172

  Fly   244 LAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLL 308
            ......|....:|.:|:.|...||:....|.:..::.:|.||||||. :|::...:||......|
Worm   173 TCAYLIAIAPYWWLYALARAGTGFSHPGIFVIAVVIGMELVGPKYRK-LASVITGLFFALGQIFL 236

  Fly   309 PWIAYFLADWKLLAIVTSAPLLLAI-----------------------------FTPFVVPESAR 344
            ...|.:..::::|.:|.::|.||.:                             |:.::||||||
Worm   237 GIEAIYFTNYQILHVVIASPALLFLSYCQKSAKNRKKIDFANFLADFLLKNRFFFSRWLVPESAR 301

  Fly   345 WLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCK-RMQEQEAQNGKYSVLDLFKSPRLRR 408
            |||||.:..:|..:|:|....||..:|...::...||.. ......|...|.:..|||::|.||:
Worm   302 WLVSQKRYKEADEVLQKAASVNGTVLPENWWEQLDDSTTGGGGAPGAPTKKLTGADLFRTPELRK 366

  Fly   409 TTLLLIVIWMAISLVFDGHVRNVGSLGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSM 473
            .||::..:|..||:|:.|.......||.||:..|..|.|.|:||..::.:::||.|||.:....:
Worm   367 RTLVVFFLWPVISMVYYGMAMKANVLGGDIYVNFIFAAFVEIPALFIVYLLIDRIGRRLILAGGL 431

  Fly   474 VLSGVFSLLATVVPVGIYSAALAIMGRFFVNIS----YNIGLQWAAEVLPTVVRAQAVAFIHIMG 534
            .::|...|:..::...: ...:||....|...|    |.....::.|:.|||:|..|:.|...:.
Worm   432 FIAGACLLVNWLMGDNV-QLWMAITQMAFTKGSITGVYAAIYTYSPELFPTVIRNTAMGFCSTIA 495

  Fly   535 YVASIIAPFV-VYLA-NISQALPLIILGILGIIGGLLALL-LPETLNHVLPQTLSDGEEFGRGQS 596
            .|.:|.|.:: :::| ...:...:|..|.:.::..::.|| ||||:...||:::.:.||....:|
Worm   496 RVGAIAASYISMWIAEQFGKVFMIIPFGCMAVLAAVMTLLFLPETMGKPLPESIEEIEEGDSYRS 560

  Fly   597 IWDFPCLAKQVDD 609
            ..:...|:|..::
Worm   561 SHEMQPLSKSTEE 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	131/527 (25%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	100/373 (27%)
Y82E9BR.16	NP_001022960.1	MFS_SLC22	107..537	CDD:340875	111/434 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010