DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42269 and UST4r

DIOPT Version :9

Sequence 1:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	597	Identity:	160/597 - (26%)
Similarity:	254/597 - (42%)	Gaps:	80/597 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 MDFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTLIPEQHWCHVPELDGLDV----- 129
            |.|.::|..:|..||:|.|..:.::..|..|......:.|...|| .|.|.||.||.:.|
  Rat     1 MAFQELLNQVGGLGRFQILQMVFVVFTSVIVVPHIIIENFTAAIP-SHRCWVPILDNVTVSDNDS 64

  Fly   130 -----EARLALSIPM-TNGEYNNCYMYDVNYTDILAQGKVMADPKW--------------PQVK- 173
                 :..|.:|||: ::...:.|..:              |.|:|              |..:
  Rat    65 RILNQDKLLKISIPLDSHLRLDKCRRF--------------AQPQWHLLDLNDTFSSITEPDTEP 115

  Fly   174 CRHGWSY---NFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPAL 235
            |..||.|   ||    ::|..||.|.||:..||.:..:..|.:||.:||::.|.::|||||...|
  Rat   116 CVDGWVYDRSNF----HSTTVTEWNLVCESQALNSVTKLSFMIGAFIGGIVNGLLSDRFGRKFIL 176

  Fly   236 IGTNMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANM-SIAI 299
            ....:...:......|..|.:.:..:||..|.:.:.....:.:|:.|:..||:.|.|..: |.|.
  Rat   177 KYALLQMAITETCAGFAPNLFIYCSLRFLAGMSLEPITVNINLLMFEWTSPKFLTMVTVLGSCAG 241

  Fly   300 FFTGAACLLPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEK 364
            .|.|  .:|..:|:...:|..|.:..|.|:...:.....:.||||||:...|..|.:..|||:..
  Rat   242 SFGG--MILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQKGLKELKKVAH 304

  Fly   365 GNGRQVPPQ--TYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGH 427
            .||.:....  |.::...|.|:  |.||...:.|..|||.:|.||:...:|..|.:...|...|.
  Rat   305 INGMKKSGDNITMEVVRTSMKK--ELEAAKMRPSPRDLFHTPILRKQIYILSFIRLLFILSGVGV 367

  Fly   428 VRNVGSLGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGIYS 492
            ..::..|..:|.....|...:.:....:...:|:..|||......|.|.|:..|.|...|..:.:
  Rat   368 AIHLQHLSNNIELLQILISVSSILFSVIGHFVLNHIGRRITQMVIMFLRGISILTAIFAPQEMET 432

  Fly   493 A--ALAIMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALP 555
            .  .:|:|......:||......|.|:|||.:||.|...|.:.|.:...:||..:.||:.|..||
  Rat   433 LRFIMAMMAEGLAALSYAANSLHANELLPTTLRATARGVIGMFGNIGFFLAPLCMMLASYSPNLP 497

  Fly   556 LIILGILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDDDEDEKRNADVE 620
            .|..|...|:.|.:.||||||.|:.||....|                   |::|..|.|    :
  Rat   498 WIFYGGFAILSGFIVLLLPETKNNPLPDCTHD-------------------VENDWKESR----Q 539

  Fly   621 EVRSQAFVRGTQ 632
            |::....::.|:
  Rat   540 EMKEDPIIKVTR 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	134/505 (27%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	92/343 (27%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	118/414 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347347
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940