Protein Alignment CG42269 and SLC22A9

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 149/557 - (26%)
• Similarity: 246/557 - (44%)
• Gaps: 66/557 - (11%)

  Fly    70 MDFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTLIP-EQHWCHVPELD-------- 125
            |.|.|:|...|:..|:|.|..:.:..|:......:..:.|...|| .:.|.|:.:.|
Human     1 MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTG 65

  Fly   126 GLDVEARLALSIPM-TNGEYNNCYMYDVNYTDILAQGKVMADPKW---------PQVK------C 174
            .|..:|.|.:|||: :|.....|..:              ..|:|         |...      |
Human    66 ALSQDALLRISIPLDSNMRPEKCRRF--------------VHPQWQLLHLNGTFPNTSDADMEPC 116

  Fly   175 RHGWSYNFTEIPY-ATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGT 238
            ..||.|:  .|.: :|:.||.:.|||..:|.:.|:.:|..|.:|||:|.|.::|||||...|...
Human   117 VDGWVYD--RISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWC 179

  Fly   239 NMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTG 303
            .:...:.|...|....|..:..:||..|.|..:..|...:|:.|:...:::..  .:::.:..:|
Human   180 YLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAM--GITLGMCPSG 242

  Fly   304 AACL-LPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKG-- 365
            .|.: |..:|:.:.||.:|.:|.|.|..:...|...:.||||||:...|.::.   ||:|.|.
Human   243 IAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEG---LKELRKAAH 304

  Fly   366 -----NGRQVPPQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFD 425
                 |.|..  .|.:|...:.|: :.:.||..|.|:.::...|.:.:...||.....|..:.:.
Human   305 RSGMKNARDT--LTLEILKSTMKK-ELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFANFMAYF 366

  Fly   426 GHVRNVGSLGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFS--LLATV-VP 487
            |...:|..||.::|...||.....|.|:.:....|....||   .|.|:|..:.:  |||.: ||
Human   367 GLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRR---ASQMLLMFLLAICLLAIIFVP 428

  Fly   488 VGIYS--AALAIMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANI 550
            ..:.:  ..||.:|.....::..:......||:||::||:|:........:|..:||.::.|:..
Human   429 QEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGALAPLMMILSVY 493

  Fly   551 SQALPLIILGILGIIGGLLALLLPETLNHVLPQTLSD 587
            |..||.||.|:...|.|...||||||.|..|..|:.|
Human   494 SPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	127/510 (25%)
		MFS	206..545	CDD:119392	92/351 (26%)
SLC22A9	NP_543142.2	Sugar_tr	11..527	CDD:331684	143/542 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153773
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940