Protein Alignment CG42269 and SLC22A7

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_011512558.1
• Gene: SLC22A7 / 10864
• HGNCID: 10971
• Length: 610
• Species: Homo sapiens
• Alignment Length: 641
• Identity: 169/641 - (26%)
• Similarity: 281/641 - (43%)
• Gaps: 132/641 - (20%)

  Fly    70 MDFDDILPLIGEFGRYQ----KLLFI--CMIPFSFFVAFVYFSQIFLTLIPEQHWCHVP----EL 124
            |.|:::|..:|.||.:|    .||.:  .::|..|.:      .|||..:| .|.|.:|    ..
Human     1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLL------PIFLAAVP-AHRCALPGAPANF 58

  Fly   125 DGLDV--EARLALSIPMTNGEYNNCYMYDVNYTDIL----------AQGKVMADPKWPQVKCRHG 177
            ...||  ||.|...   .:|..::|..:  .|...|          ::|::..:|  ..|.|..|
Human    59 SHQDVWLEAHLPRE---PDGTLSSCLRF--AYPQALPNTTLGEERQSRGELEDEP--ATVPCSQG 116

  Fly   178 WSYNFTEIPYATVATEQ----------------------------------------------NW 196
            |.|:.:|.. :|:|||.                                              :|
Human   117 WEYDHSEFS-STIATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSW 180

  Fly   197 ---------------VCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGR----IPALIGTNMMG 242
                           ||:...|...|.:.||.|.:||.:.||:::|||||    :.|.:.|.::|
Human   181 RESLGGLLSGMEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLG 245

  Fly   243 LLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILV----LEYVGPKYRTFVANMSIAIFFTG 303
            |.:....::|.    |||.|...|.|... ||::.:.:    ||::..::|| ||.:..:.|:||
Human   246 LASAASVSYVM----FAITRTLTGSALAG-FTIIVMPLGEAELEWLDVEHRT-VAGVLSSTFWTG 304

  Fly   304 AACLLPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGR 368
            ...||..:.|.:.||:.|.:..:.|....|.:.:.||||||||::||.|.:|...|....:.|||
Human   305 GVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGR 369

  Fly   369 QVPPQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGS 433
            .|...::.  .::..::...|....:.|.||||::||||..:|..:|:|..::..:.|...:|..
Human   370 PVCEDSFS--QEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSG 432

  Fly   434 LGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGI-------- 490
            |||:::.|..|....|||:..|:.:.:...|||        |:...:||.|.:..|.
Human   433 LGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRR--------LTQAGTLLGTALAFGTRLLVSSDM 489

  Fly   491 --YSAALAIMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQA 553
              :|..||:||:.|...::.....:.:|:.|||:|...:....::|.:...:||....|..:..:
Human   490 KSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLS 554

  Fly   554 LPLIILGILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDD 609
            ||.:..|.:.::....|||||||....||:|:.|.|......|:.:.....|||.:
Human   555 LPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEEMPMKQVQN 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	147/572 (26%)
		MFS	206..545	CDD:119392	106/356 (30%)
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	159/604 (26%)
		MFS	206..563	CDD:119392	110/372 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153786
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.860