Protein Alignment CG42269 and sv2b

DIOPT Version :10

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 618
• Identity: 120/618 - (19%)
• Similarity: 200/618 - (32%)
• Gaps: 245/618 - (39%)

  Fly   173 KCRHG---WSYNFTEIPYATVATEQNWVCDDAALPTYAQS-------------IFFLGAIVGGLL 221
            :|.||   |:. |..:..|.:|...........||:..:.             |.:||.::|..:
 Frog   129 ECGHGRFQWTL-FVVLGLALMADGVEVFVVGFVLPSAEKDMCLSRSNKGMLGLIVYLGMMLGAFV 192

  Fly   222 FGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNFWE----FAIMRFFVGFAFDNCFTMMYILVLE 282
            :|.:||:.||...||    :.|......:|||:|.:    |...|...||.......:::....|
 Frog   193 WGGLADKVGRKKCLI----ISLTINAAFSFVSSFVQGYGLFLFCRLISGFGIGGSLPIVFAYFSE 253

  Fly   283 YVGPKYRTFVANMSIAIFFTGA--ACLLPW-------------IAYFLADWKLLAIVTSAPLLLA 332
            ::..:.|....:.....:..||  |..:.|             ..|....|::..::...|.:.:
 Frog   254 FLAREKRGEHLSWLCMFWMIGAVYAAAMAWSIIPHYGWGFSMGTHYHFHSWRVFVVICVLPCIAS 318

  Fly   333 IFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCKRMQEQ-------EA 390
            |.....:|||.|:|:..||.|:|..|||.:...|.| ...:..::||.|..:..:|       ::
 Frog   319 IIALKFMPESPRFLLETGKHDEAWMILKNIHDTNMR-AKGEPEKVFTVSHIKTPKQPDEFIEIQS 382

  Fly   391 QNGKY------SVLDLFK----------SPRLRRTTLLLIVIWMAISLVF--------------- 424
            ..|.:      .::.:.|          |.:.|:.|:.|.|:|..:||.:
 Frog   383 STGTWFQRWFVRIMTVIKQIWENMLHCFSGQFRKNTIFLAVVWFTMSLSYYGLTVWFPDTIRYLQ 447

  Fly   425 ------------DGHVRNVGSLGLDIFFTFTL-------------------------------AC 446
                        |.:|:|..       |.|||                               .|
 Frog   448 DEDYASKVKRFTDENVKNFN-------FNFTLENQIHEDGEYYNDRFYKMKLKYVTFKDSLFDEC 505

  Fly   447 FTE-------------------------------------------------------------- 449
            :.|
 Frog   506 YFEDVTSTGSIFENCTIQNTVFYNTDLYQHKFIDCNFINVTFSQPKEGCHIDFEEDNDFLIYLVS 570

  Fly   450 -------LPADTLLTVILDRFGRRWLACSSMVLSGV--FSLLATVVPVGIYSAALAIMGRFFVNI 505
                   ||.:.:..:::|:.||..:...||::|.|  |.|                   ||.|.
 Frog   571 FLGSLSVLPGNIISALLMDKIGRIRMIAGSMLISAVCCFFL-------------------FFGNS 616

  Fly   506 -SYNIGLQ----------WAA------EVLPTVVRAQAVAFIHIMGYVA-----SIIAPFVVYLA 548
             |..||.|          |.|      |:.||..||.|...::.:..:|     ||.|.||
 Frog   617 ESAMIGWQCLFCGTSIAAWNALDVVTVELYPTNKRATAFGILNGLCKLAAIFGNSIFASFV---- 677

  Fly   549 NISQALPLIILGILGIIGGLLALLLPETLNHVL 581
            .|::.:|:::.....:.|||::|.||||...||
 Frog   678 GITKVIPILLASTALVGGGLISLRLPETRELVL 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	109/587 (19%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	120/618 (19%)