Protein Alignment CG42269 and sv2b

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 619
• Identity: 121/619 - (19%)
• Similarity: 200/619 - (32%)
• Gaps: 247/619 - (39%)

  Fly   173 KCRHG---WSYNFTEIPYATVATEQNWVCDDAALPTYAQS-------------IFFLGAIVGGLL 221
            :|.||   |:. |..:..|.:|...........||:..:.             |.:||.::|..:
 Frog   129 ECGHGRFQWTL-FVVLGLALMADGVEVFVVGFVLPSAEKDMCLSRSNKGMLGLIVYLGMMLGAFV 192

  Fly   222 FGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNFWE----FAIMRFFVGFAFDNCFTMMYILVLE 282
            :|.:||:.||...||    :.|......:|||:|.:    |...|...||.......:::....|
 Frog   193 WGGLADKVGRKKCLI----ISLTINAAFSFVSSFVQGYGLFLFCRLISGFGIGGSLPIVFAYFSE 253

  Fly   283 YVGPKYRTFVANMSIAIFFTGA--ACLLPW-------------IAYFLADWKLLAIVTSAPLLLA 332
            ::..:.|....:.....:..||  |..:.|             ..|....|::..::...|.:.:
 Frog   254 FLAREKRGEHLSWLCMFWMIGAVYAAAMAWSIIPHYGWGFSMGTHYHFHSWRVFVVICVLPCIAS 318

  Fly   333 IFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCKRMQEQ-------EA 390
            |.....:|||.|:|:..||.|:|..|||.:...|.| ...:..::||.|..:..:|       ::
 Frog   319 IIALKFMPESPRFLLETGKHDEAWMILKNIHDTNMR-AKGEPEKVFTVSHIKTPKQPDEFIEIQS 382

  Fly   391 QNGKY-----------------SVLDLFKSPRLRRTTLLLIVIWMAISLVF-------------- 424
            ..|.:                 ::|..| |.:.|:.|:.|.|:|..:||.:
 Frog   383 STGTWFQRWFVRIMTVIKQIWENMLHCF-SGQFRKNTIFLAVVWFTMSLSYYGLTVWFPDTIRYL 446

  Fly   425 -------------DGHVRNVGSLGLDIFFTFTL-------------------------------A 445
                         |.:|:|..       |.|||                               .
 Frog   447 QDEDYASKVKRFTDENVKNFN-------FNFTLENQIHEDGEYYNDRFYKMKLKYVTFKDSLFDE 504

  Fly   446 CFTE------------------------------------------------------------- 449
            |:.|
 Frog   505 CYFEDVTSTGSIFENCTIQNTVFYNTDLYQHKFIDCNFINVTFSQPKEGCHIDFEEDNDFLIYLV 569

  Fly   450 --------LPADTLLTVILDRFGRRWLACSSMVLSGV--FSLLATVVPVGIYSAALAIMGRFFVN 504
                    ||.:.:..:::|:.||..:...||::|.|  |.|                   ||.|
 Frog   570 SFLGSLSVLPGNIISALLMDKIGRIRMIAGSMLISAVCCFFL-------------------FFGN 615

  Fly   505 I-SYNIGLQ----------WAA------EVLPTVVRAQAVAFIHIMGYVA-----SIIAPFVVYL 547
            . |..||.|          |.|      |:.||..||.|...::.:..:|     ||.|.||
 Frog   616 SESAMIGWQCLFCGTSIAAWNALDVVTVELYPTNKRATAFGILNGLCKLAAIFGNSIFASFV--- 677

  Fly   548 ANISQALPLIILGILGIIGGLLALLLPETLNHVL 581
             .|::.:|:::.....:.|||::|.||||...||
 Frog   678 -GITKVIPILLASTALVGGGLISLRLPETRELVL 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	110/588 (19%)
		MFS	206..545	CDD:119392	99/545 (18%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	121/619 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910