DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42269 and slc22a13

DIOPT Version :9

Sequence 1:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_031760340.1	Gene:	slc22a13 / 100491580	XenbaseID:	XB-GENE-959647	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	519	Identity:	179/519 - (34%)
Similarity:	274/519 - (52%)	Gaps:	29/519 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 DFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTLIPEQHWCHV-------PELDGLD 128
            ||.:||..:|||||:||.|.:.:...||..||..|||:|:. ||..|.|..       |.|
Frog     3 DFAEILKNVGEFGRFQKQLVVVLSLLSFLNAFHMFSQVFME-IPVPHRCDSRWILLINPNL---- 62

  Fly   129 VEA-RLALSIPMT-NGEYNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGWSYNFTEIPYATVA 191
            .|| ||..:||.. .|:|..|.||.....|:.:..|...:...|   |:.||.|:.:| ..:|:.
Frog    63 TEAERLNYTIPRDGRGQYEQCLMYSPVQWDMESIEKFGLNSTGP---CQDGWEYDTSE-QKSTLV 123

  Fly   192 TEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNFW 256
            |:.:.||........:||::..|.::|.||||.:.||.||.|.::.:.::.|:.|:..||..:|:
Frog   124 TQFDLVCHRREQTGISQSVYMSGLLIGALLFGPLGDRIGRRPVILLSMLLQLVFGLSAAFAPHFY 188

  Fly   257 EFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFLADWKLL 321
            .:...|:.||.:.........:|..|:||...|. .|.::..:.|......|..::|.:.:|:||
Frog   189 VYTAFRWVVGTSMSGLMINNLVLGAEWVGSSRRA-CATITAHVCFAVGLMALAGVSYGIRNWRLL 252

  Fly   322 AIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCKRMQ 386
            .||:|||..|..|..:|:|||||||:::||.:|||.:|||....|.:::|......|.      :
Frog   253 QIVSSAPTALLFFYIWVLPESARWLLTKGKKEKAVKLLKKAAAMNKKEIPEDLLFQFN------E 311

  Fly   387 EQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGSLGLDIFFTFTLACFTELP 451
            |:..::|  :::|||::..||:.||::.::|...|||:.|...||||.||||:.|..:....|:|
Frog   312 EKSPKSG--NMIDLFRNKTLRKLTLVMCLVWFVNSLVYYGLSLNVGSFGLDIYLTQLVFGAVEIP 374

  Fly   452 ADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVP--VGIYSAALAIMGRFFVNISYNIGLQWA 514
            |.......:..|||:......:.|.|...|:.|.:|  :.|....||::|:|.:..|::|...:|
Frog   375 ARIGAMFAVQLFGRKPSQMFCLFLGGTVCLIITAIPRNLPIAITILAVIGKFSIASSFSICYIYA 439

  Fly   515 AEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIILGILGIIGGLLALLLPETLN 578
            |||.|||:|...|....:...||.|.||.:..|.....|:|:.|.|...||||:|..|||||.|
Frog   440 AEVFPTVIRQNGVGLASMAARVAGITAPLISLLDKYHAAIPMAIYGSGPIIGGILCFLLPETRN 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	160/482 (33%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	114/340 (34%)
slc22a13	XP_031760340.1	2A0119	12..509	CDD:273328	175/510 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I9954
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920