Protein Alignment CG42269 and slc22a5

DIOPT Version :10

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_021324939.1
• Gene: slc22a5 / 100000685
• ZFINID: ZDB-GENE-091012-1
• Length: 549
• Species: Danio rerio
• Alignment Length: 569
• Identity: 159/569 - (27%)
• Similarity: 276/569 - (48%)
• Gaps: 63/569 - (11%)

  Fly    71 DFDDILPLIGEFGRYQKLLFICMIPFSFFVAFVYFSQIFLTLIPEQHWCHVPELDGLDV---EAR 132
            ::|:....:|:.|.:...|| |::...:....::...|........|.|.|      ||   |..
Zfish     3 NYDEDTAFLGQTGPFFIRLF-CLLNLIYISTGLHGLYIVFVAASPAHRCRV------DVNLTEDW 60

  Fly   133 LALSIP---MTNG--EYNNCYMY----------------DVNYTDILAQGKVMADPKWPQVKCRH 176
            |..|.|   ::||  :.:.|:.|                .:|.|||            |:.:|..
Zfish    61 LEASAPTETLSNGDLQVSQCWRYSLQTLTNLSGQGYSPGQINITDI------------PRERCED 113

  Fly   177 GWSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMM 241
            ||.|: .::.::|:.:|.:.|||.......|.|..::|.::|.::.|.::|||||...|.|:...
Zfish   114 GWVYS-ADVYHSTIVSEWDLVCDSEWRVPLASSTLYMGYLLGSIVSGQLSDRFGRKKVLFGSLAA 177

  Fly   242 GLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAAC 306
            ..|.....:|..::..|.::.||:|....:.:...::|..|.:....|.....:...:.:.....
Zfish   178 EALLMFAQSFSPSWLIFCVLYFFIGAFQISLYITAFVLGNEVLSGSLRVLFTTLGAFLHYCVGYM 242

  Fly   307 LLPWIAYFLADWKLLAIVTSAPLLLAIFTP--FVVPESARWLVSQGKVDKAVGILKKLEKGNGRQ 369
            ||||:|:.:..|:.|..|.|.  |..::.|  :::|||.|||:|||.|.::..||:...:.|  :
Zfish   243 LLPWVAFAIRHWRTLLRVLSG--LTVVYIPLWWLIPESPRWLLSQGHVQESEAILRDAARKN--R 303

  Fly   370 VP-PQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGS 433
            || |:.  ||..|  :::|...|..|||.||:.::..:||||.:.:::||||::.:.|...|..:
Zfish   304 VPAPEV--IFKQS--QIKEAAFQKSKYSALDVLRTSNIRRTTFMCLLLWMAINIGYFGLSLNTTN 364

  Fly   434 LGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGIYSAALAI- 497
            |..|.|....|:..||:||..:.|.:|....||.:..:.:|:.|.|.||..::|..:.:.|||:
Zfish   365 LSGDPFLNCFLSAVTEVPAYIVSTFLLKSCPRRPVLSAFLVIGGGFLLLVQLIPDRLQTLALALE 429

  Fly   498 -MGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPLIILGI 561
             .|:|...:|:.:...:.||:.|||:|...:........:.||.||::::|...::.||.:::|.
Zfish   430 MAGKFGFTMSFTVVYIYTAELYPTVLRNLGMGMCSSAARIGSITAPYIIFLGTFNRHLPYVLMGS 494

  Fly   562 LGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDDD 610
            |.|...|..|.||||...|||:.|   |:..:.:|   ||...||..:|
Zfish   495 LTITASLANLFLPETFGKVLPENL---EQMQKSRS---FPGRDKQSVED 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	136/500 (27%)
slc22a5	XP_021324939.1	MFS_SLC22A4_5_OCTN1_2	104..507	CDD:340934	123/423 (29%)