Protein Alignment CG10472 and PRSS22

DIOPT Version :10

• Sequence 1: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 81/263 - (30%)
• Similarity: 123/263 - (46%)
• Gaps: 25/263 - (9%)

  Fly    33 PMPKVHGETLPSGRITGGQIAEPNQFPYQVGLLLYITGGAAWCGGTIISDRWIITAAHC-TDSLT 96
            |:|...|:.....|:.||:.:..:::|:.|.:.   ..|...|.|::::.||:|||||| .|:|.
Human   144 PVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQ---KNGTHHCAGSLLTSRWVITAAHCFKDNLN 205

  Fly    97 TG--VDVYLGAHDRTNAKEEGQQ--IIFVETKNVIVHEDWIAETITNDISLIKLPVPIEFNKYIQ 157
            ..  ..|.|||....|.....|:  :.:||...|.   .| .|....||:|::|...|:|::.:.
Human   206 KPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVY---SW-KEGACADIALVRLERSIQFSERVL 266

  Fly   158 PAKLPVKSDSYSTYGGENAIASGWGKISDSA-TGATDILQYATVPIMNNSGCSPWYF-----GLV 216
            |..||  ..|.......:...||||.|.|.. ......||...|||:::..||..|:     |.:
Human   267 PICLP--DASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPI 329

  Fly   217 AASNICI-KTTGGISTCNGDSGGPLVLD-DGSNTLIGATSFGIALGC-EVGWPGVFTRITYYLDW 278
            ....:|. ...|....|.|||||||:.. ||:..|.|..|:|  .|| |...|||:..::.:..|
Human   330 TEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWG--EGCAERNRPGVYISLSAHRSW 392

  Fly   279 IEE 281
            :|:
Human   393 VEK 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	76/246 (31%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	77/249 (31%)