Protein Alignment CG10472 and PRSS2

DIOPT Version :10

• Sequence 1: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 81/249 - (32%)
• Similarity: 120/249 - (48%)
• Gaps: 29/249 - (11%)

  Fly    46 RITGGQIAEPNQFPYQVGLLLYITGGAAWCGGTIISDRWIITAAHCTDSLTTG-----------V 99
            :|.||.|.|.|..||||.|    ..|..:|||::||::|:::|.||..|....           :
Human    23 KIVGGYICEENSVPYQVSL----NSGYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRI 83

  Fly   100 DVYLGAHDRTNAKEEGQQIIFVETKNVIVHEDWIAETITNDISLIKLPVPIEFNKYIQPAKLPVK 164
            .|.||.|: ....|..:|  |:....:|.|..:.:.|:.|||.||||..|...|..:....||..
Human    84 QVRLGEHN-IEVLEGNEQ--FINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTA 145

  Fly   165 SDSYSTYGGENAIASGWGKISDSATGATDILQYATVPIMNNSGCSPWYFGLVAASNICIK-TTGG 228
            ..:    .|..::.||||....|.....|.||....|:::.:.|...|.|.:..:..|:. ..||
Human   146 PPA----AGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGG 206

  Fly   229 ISTCNGDSGGPLVLDDGSNTLIGATSFGIALGC-EVGWPGVFTRITYYLDWIEE 281
            ..:|.||||||:|   .:..|.|..|:|  .|| :...|||:|::..|:|||::
Human   207 KDSCQGDSGGPVV---SNGELQGIVSWG--YGCAQKNRPGVYTKVYNYVDWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	79/245 (32%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	81/248 (33%)