Protein Alignment CG10472 and Cfd

DIOPT Version :10

• Sequence 1: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 292
• Identity: 83/292 - (28%)
• Similarity: 135/292 - (46%)
• Gaps: 61/292 - (20%)

  Fly     3 FACATVLLLATILGAQAVDWNSVKNLNIETPMPKVHGETLPSGRITGGQIAEPNQFPYQVGLLLY 67
            :..|.|:|.|.:..||                        |.|||.|||.|..:..||...:.:
  Rat     6 YLVALVVLEAAVCVAQ------------------------PRGRILGGQEAMAHARPYMASVQV- 45

  Fly    68 ITGGAAWCGGTIISDRWIITAAHCTDSLTTG--VDVYLGAHDRTNAKEEGQQIIFVETKNVIVHE 130
              .|...||||::.::|:::||||.|.:|..  |.|.||||..::  .|..:.:: :.::|::|.
  Rat    46 --NGTHVCGGTLVDEQWVLSAAHCMDGVTKDEVVQVLLGAHSLSS--PEPYKHLY-DVQSVVLHP 105

  Fly   131 DWIAETITNDISLIKLPVPIEFNKYIQPAKLPVKSDSYSTYGGENAIASGWGKISDSATGATDIL 195
            ....:::.:|:.|.||........:::|  ||::.:......|.....:|||.:: .|....|:|
  Rat   106 GSRPDSVEDDLMLFKLSHNASLGPHVRP--LPLQREDREVKPGTLCDVAGWGVVT-HAGRRPDVL 167

  Fly   196 QYATVPIMNNSGCS--PWYFGLVAASNICIKTTGGISTCNGDSGGPLVLDDGSNTLIGATSFGIA 258
            |..||.||:.:.|:  .::.|.:..:.:|.::... .||.||||||||..|             |
  Rat   168 QQLTVSIMDRNTCNLRTYHDGAITKNMMCAESNRR-DTCRGDSGGPLVCGD-------------A 218

  Fly   259 LGCEVGW----------PGVFTRITYYLDWIE 280
            :...|.|          ||||||:..|:.|||
  Rat   219 VEAVVTWGSRVCGNRRKPGVFTRVATYVPWIE 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	72/246 (29%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	74/248 (30%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)