Protein Alignment CG10472 and PRSS48

DIOPT Version :10

• Sequence 1: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 92/309 - (29%)
• Similarity: 137/309 - (44%)
• Gaps: 64/309 - (20%)

  Fly     5 CATVLLLATILGAQAVDWNSVKNLNIETPMPKVHGETLPSGRITGGQIAEPNQFPYQVGLLL--- 66
            ||..|||  :||.                  .|.|:.:.|.|:.|||.|...::|:||.|..
Human     6 CAFTLLL--LLGI------------------SVCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHN 50

  Fly    67 YITGGAAWCGGTIISDRWIITAAHCTDS--LTTGVDVYLGAHDRTNAKEEGQQIIFVETKNVIVH 129
            :|      |||:::|:|.|:|||||...  .|....|:||:   ....:..:::.:..:| :::|
Human    51 FI------CGGSLVSERLILTAAHCIQPTWTTFSYTVWLGS---ITVGDSRKRVKYYVSK-IVIH 105

  Fly   130 EDWIAETITNDISLIKLPVPIEFNKYIQPAKLPVKSDSYSTYGGENAI-----ASGWGKISDSA- 188
            ..:  :..|.|::|:||...:.|...|.|..||       :...:.||     .:||||:.:|:
Human   106 PKY--QDTTADVALLKLSSQVTFTSAILPICLP-------SVTKQLAIPPFCWVTGWGKVKESSD 161

  Fly   189 TGATDILQYATVPIMNNSGCSPWY--FGL--------VAASNICIKTTGGI-STCNGDSGGPLVL 242
            ......||.|.|||::...|...|  .|:        :....||...|..: .:|.|||||||..
Human   162 RDYHSALQEAEVPIIDRQACEQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSC 226

  Fly   243 D-DGSNTLIGATSFGIALGCEVGWPGVFTRITYYLDWIEEKSGVVNNGD 290
            . ||.....|..|:|  |.|....|||:|.:.||..||.......||.|
Human   227 HIDGVWIQTGVVSWG--LECGKSLPGVYTNVIYYQKWINATISRANNLD 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	77/255 (30%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	78/257 (30%)