Protein Alignment CG10472 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 90/288 - (31%)
• Similarity: 135/288 - (46%)
• Gaps: 52/288 - (18%)

  Fly    16 GAQAVDWNSVKNLNIETPMPKVHGETLPSGRITGGQIAEPNQFPYQVGL-------LLYITGGAA 73
            ||.|.|..:       .|:..|    |...||.||..|:...:|:.|.|       |:::
Human    58 GAHAEDCGT-------APLKDV----LQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHV----- 106

  Fly    74 WCGGTIISDRWIITAAHCT----DSL----TTGVDVYLGAHDRTNAKEEGQQIIFVETKNVIVHE 130
             ||||::.:||::||||||    |.|    ..|.:...|.:..|..         ::.|.:|:|.
Human   107 -CGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKK---------IKIKAIIIHP 161

  Fly   131 DWIAETITNDISLIKLPVPIEFNKYIQPAKLPVKSDSYSTY-GGENAIASGWGKISDSATGATDI 194
            ::|.|:..|||:|..|...:.:|.||||..||.  |.:... |......||||:..:.. .||:|
Human   162 NFILESYVNDIALFHLKKAVRYNDYIQPICLPF--DVFQILDGNTKCFISGWGRTKEEG-NATNI 223

  Fly   195 LQYATVPIMNNSGCSP--WYFGLVAASNICI-KTTGGISTCNGDSGGPLV--LDDGSNTLI-GAT 253
            ||.|.|..::...|:.  .|.|::..::.|. ...|...||.|||||||:  |.:.....: |.|
Human   224 LQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGIT 288

  Fly   254 SFGIALGCEVGWPGVFTRITYYLDWIEE 281
            |:|...| ..|:|||:...::|..|:.|
Human   289 SYGHGCG-RRGFPGVYIGPSFYQKWLTE 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	81/254 (32%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	82/257 (32%)