Protein Alignment CG10472 and KLK13

DIOPT Version :10

• Sequence 1: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 91/283 - (32%)
• Similarity: 137/283 - (48%)
• Gaps: 34/283 - (12%)

  Fly     6 ATVLLLATILGAQAVDWNSVKNLNIETPMPKVHGETLPSGRITGGQIAEPNQFPYQVGLLLYITG 70
            |.|:...|:..:..|...|.|.||       .:|   .||.:.||....|:..|:|..||:.
Human     5 ALVIASLTLALSGGVSQESSKVLN-------TNG---TSGFLPGGYTCFPHSQPWQAALLVQ--- 56

  Fly    71 GAAWCGGTIISDRWIITAAHCTDSLTTGVDVYLGAH--DRTNAKEEGQQIIFVETKNVIVHEDW- 132
            |...|||.::..:|::|||||   |..|:.||||.|  .|..|.|:.::::     :.|.|.::
Human    57 GRLLCGGVLVHPKWVLTAAHC---LKEGLKVYLGKHALGRVEAGEQVREVV-----HSIPHPEYR 113

  Fly   133 IAETITN---DISLIKLPVPIEFNKYIQPAKLPVKSDSYSTYGGENAIASGWGKISDSATGATDI 194
            .:.|..|   ||.|::|..|::...|||  .||:..::..| .|.....||||..:.........
Human   114 RSPTHLNHDHDIMLLELQSPVQLTGYIQ--TLPLSHNNRLT-PGTTCRVSGWGTTTSPQVNYPKT 175

  Fly   195 LQYATVPIMNNSGCSPWYFGLVAASNICIKT-TGGISTCNGDSGGPLVLDDGSNTLIGATSFGIA 258
            ||.|.:.:.::..|...|.|.:..:.:|..| .||..:|.||||||||.   :.||.|..|:|..
Human   176 LQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVC---NRTLYGIVSWGDF 237

  Fly   259 LGCEVGWPGVFTRITYYLDWIEE 281
            ...:...|||:||::.|:.||.|
Human   238 PCGQPDRPGVYTRVSRYVLWIRE 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	77/239 (32%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	80/240 (33%)