DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10472 and svh-1

DIOPT Version :9

Sequence 1:	NP_648017.1	Gene:	CG10472 / 38688	FlyBaseID:	FBgn0035670	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	258	Identity:	84/258 - (32%)
Similarity:	124/258 - (48%)	Gaps:	38/258 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 RITGGQIAEPNQFPYQVGLLLYITGGAAWCGGTIISDRWIITAAHC--TDSLTTGVDVYLGAHDR 108
            |:.||....|..||:...|....| .|..||.:|:....:||||||  .|...:..:|.:|..|
Worm   712 RVVGGFETVPGAFPWTAALRNKAT-KAHHCGASILDKTHLITAAHCFEEDERVSSYEVVVGDWD- 774

  Fly   109 TNAKEEGQQIIFVET-------KNVIVHEDWIAETITNDISLIKLPVP-IEFNKYIQPAKLPVKS 165
            .|..:..:||.:::.       |::..|          ||:::::|.| ||||:|.||..||.|.
Worm   775 NNQTDGNEQIFYLQRIHFYPLYKDIFSH----------DIAILEIPYPGIEFNEYAQPICLPSKD 829

  Fly   166 DSYSTYGGENAIASGWGKISDSATGATDILQYATVPIMNNSGC--SPWYFGLVAASNICI-KTTG 227
            ..|:.  |...:.||||.:   .....:.||.|.:||:|...|  |...:..::.|..|. ...|
Worm   830 FVYTP--GRQCVVSGWGSM---GLRYAERLQAALIPIINRFDCVNSSQIYSSMSRSAFCAGYLEG 889

  Fly   228 GISTCNGDSGGPLVL--DDGSNTLIGATSFGIALGC-EVGWPGVFTRITYYLDWIEEKSGVVN 287
            ||.:|.||||||...  :||:..|.|..|:|.  || :...||::|.:..||.||   |.::|
Worm   890 GIDSCQGDSGGPFACRREDGAFVLAGVISWGD--GCAQKKQPGIYTMVAPYLSWI---SAIIN 947

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	80/248 (32%)
CG10472	NP_648017.1	Tryp_SPc	47..282	CDD:238113	81/250 (32%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	82/253 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910