Protein Alignment CG10472 and PRSS21

DIOPT Version :10

• Sequence 1: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 86/288 - (29%)
• Similarity: 133/288 - (46%)
• Gaps: 60/288 - (20%)

  Fly    33 PMPKVHGETLPSGRITGGQIAEPNQFPYQVGLLLYITGGAAW----CGGTIISDRWIITAAHCTD 93
            |:....|..:.:.||.||:.||..::|:|..|.|       |    ||.:::|.||.:|||||
Human    28 PLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL-------WDSHVCGVSLLSHRWALTAAHC-- 83

  Fly    94 SLTTGVDVYLGAHDRTNAKEEGQQIIFVET-------------KNVIVHEDWIAETITNDISLIK 145
                 .:.|....|.:....:..|:..:.:             .|:.:...::..: ..||:|:|
Human    84 -----FETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNS-PYDIALVK 142

  Fly   146 LPVPIEFNKYIQPAKLPVKSDSYSTYGGENAI---ASGWGKI-SDSATGATDILQYATVPIMNNS 206
            |..|:.:.|:|||..|..     ||:..||..   .:|||.| .|.|..:...||...|.|:|||
Human   143 LSAPVTYTKHIQPICLQA-----STFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNS 202

  Fly   207 GCSPWY---------FG-LVAASNICIKTTGGISTCNGDSGGPLVLD-DGSNTLIGATSFGIALG 260
            .|:..:         || :|.|.|    ..||...|.|||||||..: :|....||..|:|:..|
Human   203 MCNHLFLKYSFRKDIFGDMVCAGN----AQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCG 263

  Fly   261 CEVGWPGVFTRITYYLDWIEE---KSGV 285
             ....|||:|.|:::.:||::   :||:
Human   264 -RPNRPGVYTNISHHFEWIQKLMAQSGM 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	80/264 (30%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	81/265 (31%)