Protein Alignment CG6592 and TMPRSS11D

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_004253.1
• Gene: TMPRSS11D / 9407
• HGNCID: 24059
• Length: 418
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 92/324 - (28%)
• Similarity: 145/324 - (44%)
• Gaps: 66/324 - (20%)

  Fly    57 SSSGSLEHDAEMSASNVD-----NRHIKGLGMGREMSALSEEDDREPLVLNLETTPLMEKMLPEG 116
            ::||:||.:.....:::.     |..|...|.|.::..|||:
Human   144 NNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLSEQ----------------------- 185

  Fly   117 AMAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGAN 181
                 ||.||.......:|:||.:   |....:.||||||::..::|||||.........::..:
Human   186 -----RILGGTEAEEGSWPWQVSL---RLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATS 242

  Fly   182 EIKNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSF 246
            .|.....|.::|:    .|..|:..:.....::|||:|||.::|:|.:.||.:.||      .:.
Human   243 GISTTFPKLRMRV----RNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLP------AAT 297

  Fly   247 KN----KLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGT----NICTS-GRN 302
            :|    ..|..:|||......|.:.. ||..|::||....|  |.|.||.|.    .:|.. .:.
Human   298 QNIPPGSTAYVTGWGAQEYAGHTVPE-LRQGQVRIISNDVC--NAPHSYNGAILSGMLCAGVPQG 359

  Fly   303 ARSTCNGDSGGPLVLQRRHSKKRV--LVGITSFGSIYGC-DRGYPAAFTKVASYLDWISDETGV 363
            ....|.||||||||   :...:|:  :|||.|:|...|. |:  |..:|:|.:|||||..:||:
Human   360 GVDACQGDSGGPLV---QEDSRRLWFIVGIVSWGDQCGLPDK--PGVYTRVTAYLDWIRQQTGI 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	78/247 (32%)
TMPRSS11D	NP_004253.1	SEA	48..146	CDD:460188	0/1 (0%)
		Tryp_SPc	187..415	CDD:238113	78/248 (31%)