Protein Alignment CG6592 and PRSS27

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 70/260 - (26%)
• Similarity: 116/260 - (44%)
• Gaps: 41/260 - (15%)

  Fly   120 MDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCV-DMAKRAL--VFLGAN 181
            ::|:.||.......:|:||.  :|| .|.::||||||:::.|:|||||. :.::.:|  |.|||.
Human    32 LNRMVGGQDTQEGEWPWQVS--IQR-NGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGAR 93

  Fly   182 EIKNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSF 246
            ::   .:.|...:.......:..|.:.......|:|:|.|...|.|...|.|:.||.....:.:.
Human    94 QL---VQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETG 155

  Fly   247 KNKLAIASGWGRYA-TGVHAISNVLRYVQLQIIDGRTCKSNF---------PLSYRGTNICTS-G 300
            .|  ...:|||..: ..:.....:|:.:.:.|||...|...:         |.:.:...:|.. .
Human   156 MN--CWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFE 218

  Fly   301 RNARSTCNGDSGGPLV-------LQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVASYLDWI 357
            ...:..|.||||||||       ||         .|:.|:|.  ||.| ..|..:.:|.::.:||
Human   219 EGKKDACKGDSGGPLVCLVGQSWLQ---------AGVISWGE--GCARQNRPGVYIRVTAHHNWI 272

  Fly   358  357
            Human   273  272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	69/257 (27%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	69/256 (27%)