Protein Alignment CG6592 and Tmprss5

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001346389.1
• Gene: Tmprss5 / 80893
• MGIID: 1933407
• Length: 455
• Species: Mus musculus
• Alignment Length: 336
• Identity: 82/336 - (24%)
• Similarity: 134/336 - (39%)
• Gaps: 80/336 - (23%)

  Fly    45 PAGLSTSSSSPFSSSGSLEHDAEMSASNVDNRHIKGLGMGREMSALSEEDDREPLVLNLETTPLM 109
            |.||...|..|.::..|                      ||.:|....|....||.
Mouse   182 PGGLVEESWKPSANCPS----------------------GRIVSLKCSECGARPLA--------- 215

  Fly   110 EKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAK-- 172
                       .||.||.......:|:|..::|   ...:.||.|:::...|:|||||:...:
Mouse   216 -----------SRIVGGQAVASGRWPWQASVML---GSRHTCGASVLAPHWVVTAAHCMYSFRLS 266

  Fly   173 --------RALVFLGANEIKNAKEKG-QVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFN 228
                    ..||..||..    :.:| .|..::|      :|.::.:....|:|:::|...::|:
Mouse   267 RLSSWRVHAGLVSHGAVR----QHQGTMVEKIIP------HPLYSAQNHDYDVALLQLRTPINFS 321

  Fly   229 ERIHPIQLP--KRHYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSY 291
            :.:..:.||  ::|:.:.|    ....||||.........|:.|:...:.::....|.|:...|.
Mouse   322 DTVGAVCLPAKEQHFPWGS----QCWVSGWGHTDPSHTHSSDTLQDTMVPLLSTYLCNSSCMYSG 382

  Fly   292 RGTN--ICTSGRNARS-TCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGC-DRGYPAAFTKVAS 352
            ..|:  :|....:.|: .|.||||||||.....:..  |||:.|:|.  || :...|..:.|||.
Mouse   383 ALTHRMLCAGYLDGRADACQGDSGGPLVCPSGDTWH--LVGVVSWGR--GCAEPNRPGVYAKVAE 443

  Fly   353 YLDWISDETGV 363
            :||||.|...|
Mouse   444 FLDWIHDTVQV 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	67/252 (27%)
Tmprss5	NP_001346389.1	SRCR_2	116..213	CDD:464747	10/52 (19%)
		Tryp_SPc	217..448	CDD:214473	66/251 (26%)