DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and f9b

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_001035400.1	Gene:	f9b / 678552	ZFINID:	ZDB-GENE-060421-7346	Length:	507	Species:	Danio rerio

Alignment Length:	359	Identity:	100/359 - (27%)
Similarity:	162/359 - (45%)	Gaps:	46/359 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 IALDWQQVKPMYLVSMYP----GPAGLSTSSSSPFSSSGSLEHDAEMSASNVDNRHIKGL----- 81
            :|:|.:..:|.   ..||    |.....|.:|....|:.::..:..:|       ||.|.
Zfish   160 LAVDGRSCEPR---GQYPCGRLGKIIAQTLNSRALESTETVNQNQTIS-------HINGTEYNTT 214

  Fly    82 -GMGREMSALSEEDDREPLVLNLETTPLMEKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRP 145
             ....::|.::........:.|:.::|::.. :........||.|||...|...|:|| :.|::.
Zfish   215 ESSPTDLSEMNSTSTPRNSLQNVSSSPILTN-INNTTNNKYRIVGGDEAIPGEIPWQV-VFLEKV 277

  Fly   146 KGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANEIKNAKEKGQVRLMVPS----ENFQIYPT 206
            ..:.:|||||:|::.||||||||: .|:...|:...|...:|.:|     ..|    |.:.|:|.
Zfish   278 NKIVFCGGSLLSEEWVITAAHCVE-GKQGSFFIRVGEHDVSKMEG-----TESDHGIEEYHIHPR 336

  Fly   207 WNPKR--LKDDIAIVRLPHAVSFNERIHPIQLPKRHYE---YRSFKNKLAIASGWGRYATGVHAI 266
            :|.:|  ...|||:::|...|...:...||.|..:.:.   .:|.:|.|  .|||||...| ...
Zfish   337 YNSQRSLYNHDIALLKLKKPVILFDYAVPICLGSKDFTENLLQSAENSL--VSGWGRLRYG-GIE 398

  Fly   267 SNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSGRNAR-STCNGDSGGPLVLQRRHSKKRVLVGI 330
            ||||:.|:|..:|...||.:...|......|......| ..|.||||||..  .|:.....|.||
Zfish   399 SNVLQKVELPYVDRIKCKGSSTDSISRFMFCAGYSTVRKDACQGDSGGPHA--TRYKDTWFLTGI 461

  Fly   331 TSFGSIYGCDR-GYPAAFTKVASYLDWISDETGV 363
            .|:|.  .|.: |....:|:::.|:.||::.|.:
Zfish   462 VSWGE--ECAKEGKYGIYTRISKYMAWITNITRI 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	81/245 (33%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	82/246 (33%)
f9b	NP_001035400.1	GLA	23..86	CDD:214503
		EGF_CA	88..124	CDD:238011
		FXa_inhibition	131..167	CDD:291342	2/6 (33%)
		Tryp_SPc	255..487	CDD:214473	81/245 (33%)
		Tryp_SPc	256..490	CDD:238113	82/247 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910