DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and ST14

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_068813.1	Gene:	ST14 / 6768	HGNCID:	11344	Length:	855	Species:	Homo sapiens

Alignment Length:	258	Identity:	74/258 - (28%)
Similarity:	120/258 - (46%)	Gaps:	32/258 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCV--DMAKRA------LVFL 178
            |:.||...:...:|:||. |....:| :.||.||||...:::||||.  |...|.      ..||
Human   614 RVVGGTDADEGEWPWQVS-LHALGQG-HICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFL 676

  Fly   179 GANEIKNAKEKG-QVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYE 242
            |.::.......| |.|.:   :....:|.:|......|||::.|.....::..:.||.||...:.
Human   677 GLHDQSQRSAPGVQERRL---KRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHV 738

  Fly   243 YRSFKNKLAIASGWG--RYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICT---SGRN 302
            :.:  .|....:|||  :|. |..|:  :|:..::::|:..||::..|.......:|.   ||
Human   739 FPA--GKAIWVTGWGHTQYG-GTGAL--ILQKGEIRVINQTTCENLLPQQITPRMMCVGFLSG-- 796

  Fly   303 ARSTCNGDSGGPLVLQRRHSKKRVL-VGITSFGSIYGC-DRGYPAAFTKVASYLDWISDETGV 363
            ...:|.||||||  |....:..|:. .|:.|:|.  || .|..|..:|::..:.|||.:.|||
Human   797 GVDSCQGDSGGP--LSSVEADGRIFQAGVVSWGD--GCAQRNKPGVYTRLPLFRDWIKENTGV 855

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	69/250 (28%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	70/251 (28%)
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SEA	88..>171	CDD:307516
		CUB	227..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	488..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	70/252 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910