Protein Alignment CG6592 and PRSS56

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 105/389 - (26%)
• Similarity: 163/389 - (41%)
• Gaps: 68/389 - (17%)

  Fly    35 PMYLVSMYPGPAGLSTSSSSPFSSSGSLEHDAEMS----ASNVDNRHIKGLGMGREMSALSEEDD 95
            |:|  :..| |:.|...|:....:..:.:..|:.:    |..:.:|..:..|.||.......:|.
Human    21 PLY--TRLP-PSALQVLSAQGTQALQAAQRSAQWAINRVAMEIQHRSHECRGSGRPRPQALLQDP 82

  Fly    96 REPLVLNLETTPLMEKMLPEGA---MAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLIS 157
            .||       .|..|:. |..|   .|..||.||....|..:|:.|.:.|   .|...|||.|::
Human    83 PEP-------GPCGERR-PSTANVTRAHGRIVGGSAAPPGAWPWLVRLQL---GGQPLCGGVLVA 136

  Fly   158 DKHVITAAHCVDMAKRALVFLGA-NEI-----KNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDI 216
            ...|:|||||         |:|| ||:     .....:|:....||......:|.::|:...:|:
Human   137 ASWVLTAAHC---------FVGAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDL 192

  Fly   217 AIVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGR-YATGVHAISNVLRYVQLQIIDG 280
            |:|:|...||......|:.||:...|..: ....||| |||. :..|..|  ..:|..::.::..
Human   193 ALVQLWTPVSPGGSARPVCLPQEPQEPPA-GTACAIA-GWGALFEDGPEA--EAVREARVPLLST 253

  Fly   281 RTCKSNFPLSYRGTNICTSGRNAR--STCNGDSGGPLVLQRRHSKKR-VLVGITSFGSIYGC-DR 341
            .||:.......|.:.:..:|..|.  .:|.|||||||.......:.| ||.|:||:|.  || :.
Human   254 DTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGD--GCGEP 316

  Fly   342 GYPAAFTKVASYLDWISDETGVSAHQDTTEAIFFDQYVREYGKPRQSRRLETEEQLEDDVPDEL 405
            |.|..:|:||.:.||:.::...::                     .||.....|.|..|.|.||
Human   317 GKPGVYTRVAVFKDWLQEQMSAAS---------------------SSREPSCRELLAWDPPQEL 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	76/246 (31%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	76/247 (31%)
		PksD	<178..600	CDD:442550	58/209 (28%)