Protein Alignment CG6592 and TPSB2

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 77/282 - (27%)
• Similarity: 120/282 - (42%)
• Gaps: 72/282 - (25%)

  Fly   114 PEGAMAMDR--IFGGDVGNPHCFPYQVGMLLQRPKGLYW---CGGSLISDKHVITAAHCVDMAKR 173
            |....|:.|  |.||.......:|:||.:   |.:..||   ||||||..:.|:||||||....:
Human    20 PAPGQALQRVGIVGGQEAPRSKWPWQVSL---RVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVK 81

  Fly   174 ALVFLGANEIKNAKEKGQVR--------LMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNER 230
            .|..|          :.|:|        .::|.....::|.:...::..|||::.|...|:.:..
Human    82 DLAAL----------RVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSH 136

  Fly   231 IHPIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAISN--------VLRYVQLQIIDGRTCKSNF 287
            :|.:.||.....:         ..|...:.||...:.|        .|:.|::.|::...|.:.:
Human   137 VHTVTLPPASETF---------PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKY 192

  Fly   288 PL-SYRGTNI--------CTSGRNARSTCNGDSGGPLV-------LQRRHSKKRVLVGITSFGSI 336
            .| :|.|.::        | :|...|.:|.||||||||       ||         .|:.|:|.
Human   193 HLGAYTGDDVRIVRDDMLC-AGNTRRDSCQGDSGGPLVCKVNGTWLQ---------AGVVSWGE- 246

  Fly   337 YGCDR-GYPAAFTKVASYLDWI 357
             ||.: ..|..:|:|..|||||
Human   247 -GCAQPNRPGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	74/271 (27%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	74/271 (27%)