Protein Alignment CG6592 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 88/350 - (25%)
• Similarity: 150/350 - (42%)
• Gaps: 70/350 - (20%)

  Fly    81 LGMGREMSALSEEDDREPLVLNLETTPLMEKMLPE-------GAMAMDRIFGGDVGNPHCFPYQV 138
            :|..:::..:...::.:.|.:...:.|.:...|..       .::...|:.|.:..:...:|:||
Human   156 IGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQV 220

  Fly   139 GMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVF-----LGANEIKNAKEKGQVRLMVPS 198
            .:...:.   :.||||::....|:|||||  ..|...||     .|::::.:.......::::..
Human   221 SIQYDKQ---HVCGGSILDPHWVLTAAHC--FRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIE 280

  Fly   199 ENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKLAIAS-----GWGR 258
            .| .:||..|      |||:::|...::|:..:.||.||       .|..:|..|:     |||.
Human   281 FN-PMYPKDN------DIALMKLQFPLTFSGTVRPICLP-------FFDEELTPATPLWIIGWGF 331

  Fly   259 YATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRG----TNICTS-GRNARSTCNGDSGGPLVLQ 318
            .......:|::|....:|:||...|  |...:|:|    ..:|.. ......||.|||||||:.|
Human   332 TKQNGGKMSDILLQASVQVIDSTRC--NADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQ 394

  Fly   319 RRHSKKRVLVGITSFGSIYGC-DRGYPAAFTKVASYLDWI--------------SDETGVSAHQD 368
               |.:..:|||.|:|  ||| ....|..:|||::||:||              |..||:...|.
Human   395 ---SDQWHVVGIVSWG--YGCGGPSTPGVYTKVSAYLNWIYNVWKDRTIQRSCNSPGTGLVIQQP 454

  Fly   369 TTEAIFFDQYVREYGKPRQSRRLET 393
            ...       :.|....|.:.||.|
Human   455 AVP-------LMELRSARHTHRLTT 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	74/265 (28%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597	4/40 (10%)
		Tryp_SPc	204..429	CDD:214473	73/250 (29%)