Protein Alignment CG6592 and KLK6

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 61/227 - (26%)
• Similarity: 97/227 - (42%)
• Gaps: 27/227 - (11%)

  Fly   135 PYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANEIK---NAKEKGQVRLMV 196
            |||..:.   ..|...|||.||....|:|||||  ......||||.:.::   :::|:..|...|
Human    34 PYQAALY---TSGHLLCGGVLIHPLWVLTAAHC--KKPNLQVFLGKHNLRQRESSQEQSSVVRAV 93

  Fly   197 PSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYAT 261
                  |:|.::......||.::||......:|.|.|:.|.:.    .|.........|||:.|.
Human    94 ------IHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERD----CSANTTSCHILGWGKTAD 148

  Fly   262 GVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSG-RNARSTCNGDSGGPLVLQRRHSKKR 325
            |  ...:.::...:.::....|:..:|.......:|... :..:.:|.||||||||....
Human   149 G--DFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDH----- 206

  Fly   326 VLVGITSFGSIYGCDRGYPAAFTKVASYLDWI 357
             |.|:.|:|:|....:..|..:|.|..|.:||
Human   207 -LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	61/227 (27%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	59/225 (26%)