DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6592 and MASP1

DIOPT Version :9

Sequence 1:NP_648016.1 Gene:CG6592 / 38687 FlyBaseID:FBgn0035669 Length:438 Species:Drosophila melanogaster
Sequence 2:XP_011511291.1 Gene:MASP1 / 5648 HGNCID:6901 Length:735 Species:Homo sapiens


Alignment Length:284 Identity:73/284 - (25%)
Similarity:137/284 - (48%) Gaps:57/284 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 RIFGGDVGNPHCFPYQVGMLLQR----PKGLYWCGGSLISDKHVITAAHCVDMAKR--------- 173
            ||.||....|..||:|..::::.    |...::..|:|:|...::||||.:...:|         
Human   456 RIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVIPVSK 520

  Fly   174 --ALVFLGANEIKN---AKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHP 233
              ..|:||.:::::   |......|::       ::|.:|.:....|||:|:|...|.....:.|
Human   521 EHVTVYLGLHDVRDKSGAVNSSAARVV-------LHPDFNIQNYNHDIALVQLQEPVPLGPHVMP 578

  Fly   234 IQLPKRHYEYRSFKNKLAIASGWG----------RYATGVHAISNVLRYVQLQIIDGRTCKSNFP 288
            :.||:...|..: .:.|.:.:|||          ..::|...:|:||:||:|.::....||:::.
Human   579 VCLPRLEPEGPA-PHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYE 642

  Fly   289 L---SYRGT-NICTSG--RNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFG--------SIYGC 339
            .   :|..| |:..:|  ...:.||.|||||..|:....|::.|:.|:.|:|        .:|| 
Human   643 SRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYG- 706

  Fly   340 DRGYPAAFTKVASYLDWISDETGV 363
                  .:|||::|:||:.::.|:
Human   707 ------VYTKVSNYVDWVWEQMGL 724

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6592NP_648016.1 Tryp_SPc 122..357 CDD:214473 71/276 (26%)
Tryp_SPc 123..359 CDD:238113 71/277 (26%)
MASP1XP_011511291.1 CUB 35..144 CDD:238001
FXa_inhibition 160..188 CDD:291342
CUB 192..301 CDD:278839
Sushi 308..369 CDD:278512
CCP 374..439 CDD:153056
Tryp_SPc 456..718 CDD:214473 71/276 (26%)
Tryp_SPc 457..718 CDD:238113 70/275 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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