Protein Alignment CG6592 and PRSS1

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 70/260 - (26%)
• Similarity: 117/260 - (45%)
• Gaps: 28/260 - (10%)

  Fly   107 PLMEKMLPEGAMAM-----DRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAH 166
            ||:.......|:|.     |:|.||.....:..||||.:    ..|.::||||||:::.|::|.|
Human     3 PLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSL----NSGYHFCGGSLINEQWVVSAGH 63

  Fly   167 CVDMAKRALVFLGANEIKNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERI 231
            |  ...|..|.||.:.|:..:...|   .:.:.....:|.::.|.|.:||.:::|......|.|:
Human    64 C--YKSRIQVRLGEHNIEVLEGNEQ---FINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARV 123

  Fly   232 HPIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNI 296
            ..|.||..    ........:.||||..|:......:.|:.:...::....|::::|........
Human   124 STISLPTA----PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMF 184

  Fly   297 CTSG-RNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGC-DRGYPAAFTKVASYLDWISD 359
            |... ...:.:|.||||||:|...:      |.|:.|:|.  || .:..|..:|||.:|:.||.:
Human   185 CVGFLEGGKDSCQGDSGGPVVCNGQ------LQGVVSWGD--GCAQKNKPGVYTKVYNYVKWIKN 241

  Fly   360  359
            Human   242  241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	65/237 (27%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	63/236 (27%)