Protein Alignment CG6592 and KLK15

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 78/260 - (30%)
• Similarity: 118/260 - (45%)
• Gaps: 49/260 - (18%)

  Fly   121 DRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANEIKN 185
            |::..||...||..|:||.:.   .:|.:.||.||||...|::||||.....|  |.||.:.::.
Human    20 DKLLEGDECAPHSQPWQVALY---ERGRFNCGASLISPHWVLSAAHCQSRFMR--VRLGEHNLRK 79

  Fly   186 AKEKGQVRL---MVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKR--HYEYRS 245
            .....|:|.   ::|      :|.:..:..::||.::||......|.::.|..||.|  |
Human    80 RDGPEQLRTTSRVIP------HPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPH----- 133

  Fly   246 FKNKLAIASGWGRYATGVH-------------AISNVLRYVQLQIIDGRTCKSNFPLSYRGTNIC 297
             ..:..:.||||..:   |             ::.:.|....:.||...:|..::|.....|.:|
Human   134 -PGEACVVSGWGLVS---HNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVC 194

  Fly   298 --TSGRNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVASYLDWISD 359
              ..||.|.| |.||||||||.      ..:|.||.|:|.: .||. ..|..:|||..||:||.:
Human   195 AGAEGRGAES-CEGDSGGPLVC------GGILQGIVSWGDV-PCDNTTKPGVYTKVCHYLEWIRE 251

  Fly   360  359
            Human   252  251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	77/256 (30%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	75/251 (30%)