DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and Hgfac

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_006504094.1	Gene:	Hgfac / 54426	MGIID:	1859281	Length:	658	Species:	Mus musculus

Alignment Length:	376	Identity:	104/376 - (27%)
Similarity:	157/376 - (41%)	Gaps:	78/376 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 YPGPAGLSTSSSSPFSSSGSLEHDAEMSASNVDNRHIKGLGMGR----------------EMSAL 90
            |.|.|..:.|..|..:.:..|.:. |:...:|....:.|||...                :.:||
Mouse   291 YRGVASTAASGLSCLAWNSDLLYQ-ELHVDSVAAAVLLGLGPHAYCRNPDKDERPWCYVVKDNAL 354

  Fly    91 SEEDDR----EPLVLNLETTPLMEKMLPEGAMAM---------------DRIFGGDVGNPHCFPY 136
            |.|..|    |.|......||.:...|||.|.|:               .||.||....|...|:
Mouse   355 SWEYCRLTACESLARVHSQTPEILAALPESAPAVRPTCGKRHKKRTFLRPRIIGGSSSLPGSHPW 419

  Fly   137 QVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMA---KRALVFLGA---NEIKNAKEKGQVRLM 195
            ...:.:    |..:|.|||:....|::||||...:   ....|.||.   |...:..:...:...
Mouse   420 LAAIYI----GNSFCAGSLVHTCWVVSAAHCFANSPPRDSITVVLGQHFFNRTTDVTQTFGIEKY 480

  Fly   196 VPSENFQIYPTWNPKRLKDDIAIVRLPH-----AVSFNERIHPIQLPKRHYEYRSFKNKLAIASG 255
            ||   :.:|..:||.  ..|:.::||..     ||. ::.:.||.||:....:.: .:|..|| |
Mouse   481 VP---YTLYSVFNPN--NHDLVLIRLKKKGERCAVR-SQFVQPICLPEAGSSFPT-GHKCQIA-G 537

  Fly   256 WG-----RYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNI-----CTSGRNARS-TCNG 309
            ||     :.:|.|.:.||.|....:.::....|.|  |..| |.:|     |....:.:| .|.|
Mouse   538 WGHMDEMQSSTDVSSYSNSLLEALVPLVADHKCSS--PEVY-GADISPNMLCAGYFDCKSDACQG 599

  Fly   310 DSGGPLVLQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVASYLDWISD 359
            |||||||.::  :....|.||.|:|.  ||.| ..|..:|:||:|:|||:|
Mouse   600 DSGGPLVCEK--NGVAYLYGIISWGD--GCGRLNKPGVYTRVANYVDWIND 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	76/257 (30%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	77/258 (30%)
Hgfac	XP_006504094.1	FN2	99..145	CDD:128373
		EGF_CA	159..194	CDD:238011
		FN1	197..237	CDD:238018
		EGF_CA	242..275	CDD:238011
		Kringle	283..364	CDD:333799	16/73 (22%)
		Tryp_SPc	406..646	CDD:238113	77/258 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000