DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6592 and PLG

DIOPT Version :9

Sequence 1:NP_648016.1 Gene:CG6592 / 38687 FlyBaseID:FBgn0035669 Length:438 Species:Drosophila melanogaster
Sequence 2:NP_000292.1 Gene:PLG / 5340 HGNCID:9071 Length:810 Species:Homo sapiens


Alignment Length:244 Identity:80/244 - (32%)
Similarity:127/244 - (52%) Gaps:28/244 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRA---LVFLGANEI 183
            |:.||.|.:||.:|:||.  |:...|:::|||:|||.:.|:|||||::.:.|.   .|.|||::.
Human   580 RVVGGCVAHPHSWPWQVS--LRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQE 642

  Fly   184 KNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFKN 248
            .|.:.  .|:.:..|..| :.||      :.|||:::|.......:::.|..||..:|....  .
Human   643 VNLEP--HVQEIEVSRLF-LEPT------RKDIALLKLSSPAVITDKVIPACLPSPNYVVAD--R 696

  Fly   249 KLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYR--GTNICTSGRNARST--CNG 309
            .....:|||. ..|... :.:|:..||.:|:.:.|.....|:.|  .|.:| :|..|..|  |.|
Human   697 TECFITGWGE-TQGTFG-AGLLKEAQLPVIENKVCNRYEFLNGRVQSTELC-AGHLAGGTDSCQG 758

  Fly   310 DSGGPLVLQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVASYLDWI 357
            |||||||...:  .|.:|.|:||:|  .||.| ..|..:.:|:.::.||
Human   759 DSGGPLVCFEK--DKYILQGVTSWG--LGCARPNKPGVYVRVSRFVTWI 803

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6592NP_648016.1 Tryp_SPc 122..357 CDD:214473 78/242 (32%)
Tryp_SPc 123..359 CDD:238113 79/243 (33%)
PLGNP_000292.1 PAN_AP_HGF <38..97 CDD:238532
KR 101..183 CDD:214527
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 126..145
KR 183..263 CDD:214527
KR 273..354 CDD:214527
KR 375..456 CDD:214527
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 396..416
KR 479..560 CDD:214527
Tryp_SPc 580..803 CDD:214473 78/242 (32%)
Tryp_SPc 581..804 CDD:238113 79/243 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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