Protein Alignment CG6592 and ACR

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 87/275 - (31%)
• Similarity: 123/275 - (44%)
• Gaps: 41/275 - (14%)

  Fly   114 PEGAMAMDRIFGGDVGNPHCFPYQVGMLL--QRPKGLYWCGGSLISDKHVITAAHCV----DMAK 172
            |:|.:   ||.||.......:|:.|.:.:  ......:.|||||::.:.|:|||||.    ::..
Human    37 PQGGV---RIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHD 98

  Fly   173 RALVFLGANEI-----KNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIH 232
            ..||| ||.||     |..|...|.|.:   |...|:..:|.....:|||:|.:...:|....|.
Human    99 WRLVF-GAKEITYGNNKPVKAPLQERYV---EKIIIHEKYNSATEGNDIALVEITPPISCGRFIG 159

  Fly   233 PIQLPKRHYEYRSFKNKLAIAS------GWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSY 291
            |..||       .||..|...|      |||.........|::|...::.:||...|.|.  ..|
Human   160 PGCLP-------HFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNST--QWY 215

  Fly   292 RG----TNICTSGRNAR-STCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRG-YPAAFTKV 350
            .|    ||:|......: .||.|||||||:.:.......|:|||||:|  .||.|. .|..:|..
Human   216 NGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWG--VGCARAKRPGIYTAT 278

  Fly   351 ASYLDWISDETGVSA 365
            ..||:||:.:.|.:|
Human   279 WPYLNWIASKIGSNA 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	82/258 (32%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	81/257 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421