Protein Alignment CG6592 and KLK12

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 70/248 - (28%)
• Similarity: 104/248 - (41%)
• Gaps: 43/248 - (17%)

  Fly   119 AMDRIFGGDVGNPHCFPYQVGMLLQRPKGL-YWCGGSLISDKHVITAAHCVDMAKRALVFLGANE 182
            |..:||.|.....:..|:|||:.    :|. ..|||.||..:.|:|||||  ...|..|.||.:.
Human    18 ATPKIFNGTECGRNSQPWQVGLF----EGTSLRCGGVLIDHRWVLTAAHC--SGSRYWVRLGEHS 76

  Fly   183 IKNAKEKGQVRLMVPSENFQIYPTWNPKRL------KDDIAIVRLPHAVSFNERIHPIQLPKRHY 241
            :.......|:|    ...|.:   .:|..|      :.|:.::||...|.....:.|:.||
Human    77 LSQLDWTEQIR----HSGFSV---THPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLP---- 130

  Fly   242 EYRSFKNKLAIA------SGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSG 300
                  |..|.|      ||||......:...::|:.:.|.|:...||...:|.......:|..|
Human   131 ------NDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGG 189

  Fly   301 RNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVAS 352
            ...:..|.||||||||.      ..||.|:.|:||:..|.: |.|..:|.:.:
Human   190 VPGQDACQGDSGGPLVC------GGVLQGLVSWGSVGPCGQDGIPGVYTYICN 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	69/244 (28%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	69/242 (29%)