Protein Alignment CG6592 and KLK14

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 68/260 - (26%)
• Similarity: 114/260 - (43%)
• Gaps: 42/260 - (16%)

  Fly   117 AMAM-------DRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRA 174
            |:||       ::|.||........|:|.. ||..|:..:.|||:|:|.:.|||||||   .:..
Human    12 AIAMTQSQEDENKIIGGHTCTRSSQPWQAA-LLAGPRRRFLCGGALLSGQWVITAAHC---GRPI 72

  Fly   175 L-VFLGANEIKNAKEKGQVRLMVPSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPK 238
            | |.||.:.::..:...||..:|....   :|.:|.:...:|:.:::|.........:.||::.:
Human    73 LQVALGKHNLRRWEATQQVLRVVRQVT---HPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQ 134

  Fly   239 RHYEYRSFKNKLAIA--------SGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTN 295
                        |.|        ||||..::.:......|:.|.:.|.....|:..:|.:.....
Human   135 ------------ACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGM 187

  Fly   296 ICTS-GRNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDWISD 359
            :|.. .:..:.:|.||||||||.:.:      |.|:.|:|.......|||..:|.:..|..||.:
Human   188 VCAGVPQGGKDSCQGDSGGPLVCRGQ------LQGLVSWGMERCALPGYPGVYTNLCKYRSWIEE 246

  Fly   360  359
            Human   247  246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	65/245 (27%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	65/247 (26%)