DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and CG31326

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	356	Identity:	92/356 - (25%)
Similarity:	145/356 - (40%)	Gaps:	78/356 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 QQVKPMYLVSMYPGPAGLSTSSSSPFSSSGSLEHDAEMSASNV---DNRHIKGLGMGREMSALSE 92
            ||..|...::..|..........:|..|..:....|..|..::   .|....|:..|||.::
  Fly   208 QQANPNRGITSQPEIPSPVPQRPTPNPSRSNAPQQAVRSPVDLVPQQNPSSNGIPCGRERAS--- 269

  Fly    93 EDDREPLVLNLETTPLM--EKMLPEGAMAMDRIFGGDVGNPHCFPYQVGMLLQRPKG--LYWCGG 153
                        ||||:  .|.|..|.:                |:.|.:..:|...  .:.|||
  Fly   270 ------------TTPLIFQGKSLQRGQL----------------PWLVAIFERRESNGPAFICGG 306

  Fly   154 SLISDKHVITAAHCV-----DM-AKRALVFLGANEI---KNAKEKGQVRLMVPSENFQIYPTWNP 209
            :|||...|::||||.     |: |.|..|.||.|.:   .:.:.:|..:|:: .||||.
  Fly   307 TLISTSTVLSAAHCFRAPGRDLPASRLAVSLGRNTLAIHSDGEFRGVSQLII-HENFQF------ 364

  Fly   210 KRLKD-DIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKL-------AIASGWGRYATGVHAI 266
            |:..: |:|:|||...|.:.:.|.||.|       .|..|::       :..:|||...||. ..
  Fly   365 KQFTEADLALVRLDEPVRYTDYIVPICL-------WSTSNRMDLPQGLKSYVAGWGPDETGT-GN 421

  Fly   267 SNVLRYVQLQIIDGRTCKSNFP-LSYRGTNICTSGRNARSTCNGDSGGPLVLQRRHSKKRVLVGI 330
            :.|.:...|.|:....|....| :..:.:::|.. :.....|..|.||||:|  |.....||.|:
  Fly   422 TEVSKVTDLNIVSEANCALELPHVLVQPSSLCAK-KTGAGPCASDGGGPLML--REQDVWVLRGV 483

  Fly   331 TSFGSI----YGCDRGYPAAFTKVASYLDWI 357
            .|.|.|    ..|:...|:.||.||.:::|:
  Fly   484 ISGGVINEKENTCELSKPSVFTDVAKHIEWV 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	71/258 (28%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	72/259 (28%)
CG31326	NP_650344.2	GD_N	26..126	CDD:292649
		Tryp_SPc	277..517	CDD:238113	75/272 (28%)
		Tryp_SPc	277..514	CDD:214473	74/270 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471168
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940