Protein Alignment CG6592 and KLK2

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 76/261 - (29%)
• Similarity: 109/261 - (41%)
• Gaps: 38/261 - (14%)

  Fly   116 GAMAM--DRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFL 178
            ||:.:  .||.||.....|..|:||.:.   ..|...|||.|:..:.|:|||||  :.|.:.|:|
Human    16 GAVPLIQSRIVGGWECEKHSQPWQVAVY---SHGWAHCGGVLVHPQWVLTAAHC--LKKNSQVWL 75

  Fly   179 GANEIKNAKEKGQVRLMVPSENFQIYPTWNPKRLK-----------DDIAIVRLPHAVSFNERIH 232
            |.:.:...::.||   .||..:...:|.:|...||           .|:.::||.......:.:.
Human    76 GRHNLFEPEDTGQ---RVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 137

  Fly   233 PIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNIC 297
            .:.||.:    .........|||||............|:.|.|.::....|...:........:|
Human   138 VLGLPTQ----EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 198

  Fly   298 ----TSGRNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDWIS 358
                |.|::   ||.||||||||.      ..||.||||:|.........||.:|||..|..||.
Human   199 AGLWTGGKD---TCGGDSGGPLVC------NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIK 254

  Fly   359 D 359
            |
Human   255 D 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	72/250 (29%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	73/252 (29%)