Protein Alignment CG6592 and KLK1

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 67/251 - (26%)
• Similarity: 112/251 - (44%)
• Gaps: 31/251 - (12%)

  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANEIKNA 186
            ||.||.....|..|:|..:.   ....:.|||.|:..:.|:|||||:  :....::||.:.:.:
Human    24 RIVGGWECEQHSQPWQAALY---HFSTFQCGGILVHRQWVLTAAHCI--SDNYQLWLGRHNLFD- 82

  Fly   187 KEKGQVRLMVPSENFQIYPTWNPKRLKD-----------DIAIVRLPH-AVSFNERIHPIQLPKR 239
             ::...:.:..||:|. :|.:|...|::           |:.::||.. |.:..:.:..::||..
Human    83 -DENTAQFVHVSESFP-HPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPTE 145

  Fly   240 HYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSG-RNA 303
            ..|..|    ..:|||||.......:..:.|:.|.|:|:....||...........:|... ...
Human   146 EPEVGS----TCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGG 206

  Fly   304 RSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDWISD 359
            :.||.|||||||:..      .||.|:||:|.:.......|:...:|.||:.||.|
Human   207 KDTCVGDSGGPLMCD------GVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIED 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	65/248 (26%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	66/250 (26%)