Protein Alignment CG6592 and KLK3

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 76/260 - (29%)
• Similarity: 114/260 - (43%)
• Gaps: 42/260 - (16%)

  Fly   118 MAMDRIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANE 182
            :.:.||.||.....|..|:||   |...:|...|||.|:..:.|:|||||:  ..::::.||.:.
Human    20 LILSRIVGGWECEKHSQPWQV---LVASRGRAVCGGVLVHPQWVLTAAHCI--RNKSVILLGRHS 79

  Fly   183 IKNAKEKGQVRLMVPSENFQI-----YPTWNPKRLKD-----------DIAIVRLPHAVSFNERI 231
            :.:.::.|||        ||:     :|.::...||:           |:.::||.......:.:
Human    80 LFHPEDTGQV--------FQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136

  Fly   232 HPIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNI 296
            ..:.||.:    .........|||||............|:.|.|.:|....|....|.......:
Human   137 KVMDLPTQ----EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197

  Fly   297 CTSGR--NARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDWISD 359
            | :||  ..:|||:||||||||.      ..||.||||:||........|:.:|||..|..||.|
Human   198 C-AGRWTGGKSTCSGDSGGPLVC------NGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 255

  Fly   360  359
            Human   256  255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	74/253 (29%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	75/255 (29%)