Protein Alignment CG6592 and OVCH2

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_047282834.1
• Gene: OVCH2 / 341277
• HGNCID: 29970
• Length: 569
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 96/302 - (31%)
• Similarity: 142/302 - (47%)
• Gaps: 65/302 - (21%)

  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVF---LGANEI 183
            ||.||.......:|:||. |.||.|.:  ||||::|.:.|||||||:  |.|.:|.   :.|.|.
Human    55 RILGGSQVEKGSYPWQVS-LKQRQKHI--CGGSIVSPQWVITAAHCI--ANRNIVSTLNVTAGEY 114

  Fly   184 K-NAKEKGQVRLMVPSENFQIYPTWNPKRLKD-DIAIVRLPHAVSFNERIHPIQLPKRHYEYRSF 246
            . :..:.|:..|.:  |...|:|.::.|:..| |||::::..|..|...:.||.||:...::.:
Human   115 DLSQTDPGEQTLTI--ETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEA- 176

  Fly   247 KNKLAIASGWGRYATGVHAISNVLRYVQLQIIDGRTCKSNF-----PLSYRGTNICT----SGRN 302
             ..:...:||||...| ..:|.||:.|.|.|:....|.:..     |:|.: |.:||    .||:
Human   177 -GFICTTAGWGRLTEG-GVLSQVLQEVNLPILTWEECVAALLTLKRPISGK-TFLCTGFPDGGRD 238

  Fly   303 ARSTCNGDSGGPLVLQRRHSKKR--VLVGITSFGSIYGCDRGY-----------PAAFTKVASYL 354
            |   |.|||||.|:.:   :||.  .|.|:||:|  .||.||:           |..||.::..|
Human   239 A---CQGDSGGSLMCR---NKKGAWTLAGVTSWG--LGCGRGWRNNVRKSDQGSPGIFTDISKVL 295

  Fly   355 DWISDETGVSAHQDTTEAIFFDQYVREYGKPRQSRRLETEEQ 396
            .||.:      |..|             |..|:|.|....||
Human   296 PWIHE------HIQT-------------GNRRKSSRAWCSEQ 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	87/262 (33%)
OVCH2	XP_047282834.1	Tryp_SPc	56..301	CDD:238113	87/269 (32%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001