DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and prss60.3

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	256	Identity:	83/256 - (32%)
Similarity:	130/256 - (50%)	Gaps:	30/256 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 RIFGGDVGNPHCFPYQVGMLLQRPK-GLYWCGGSLISDKHVITAAHCVDMAKRA--LVFLGANEI 183
            ||.||...:|..:|:||.  |..|| |.::|||||||.:.|:|||||:......  :|:||
Zfish    35 RIVGGVNASPGSWPWQVS--LHSPKYGGHFCGGSLISSEWVLTAAHCLSGVSETTLVVYLG---- 93

  Fly   184 KNAKEKGQVRLMVPSENFQ---IYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRS 245
             ...::| :.:...|.|..   ::.::|.....:|||::||..||:|...|.|:.|..::..|.:
Zfish    94 -RRTQQG-INIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIRPVCLAAQNSVYSA 156

  Fly   246 FKNKLAIASGWGRYATGVH-AISNVLRYVQLQIIDGRTCKSNFPLSYRGT---NICTSG--RNAR 304
              ...:..:|||....||: ....:|:...:.::....|.:   |...||   |:..:|  :..:
Zfish   157 --GTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRCNA---LLGSGTVTNNMICAGLTQGGK 216

  Fly   305 STCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGC-DRGYPAAFTKVASYLDWISDETGVS 364
            .||.||||||:|  .|.....|..||||:|  ||| |...|..:|:|:.|..|||.:..::
Zfish   217 DTCQGDSGGPMV--TRLCTVWVQAGITSWG--YGCADPNSPGVYTRVSQYQSWISSKISLN 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	80/247 (32%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	81/248 (33%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	82/249 (33%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000