DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6592 and f2

DIOPT Version :9

Sequence 1:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_005169022.1	Gene:	f2 / 325881	ZFINID:	ZDB-GENE-030131-4606	Length:	635	Species:	Danio rerio

Alignment Length:	319	Identity:	88/319 - (27%)
Similarity:	142/319 - (44%)	Gaps:	58/319 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 GMGREMSALSEEDDREPLV---------LNLETTPLMEKM----LPEGAMAM----DRIFGGDVG 129
            |.|||.:.|   |.|:...         |:....||.||:    ..|..:.|    .||.|||..
Zfish   319 GGGRERTTL---DQRKAFFNPRSFGNGELDCGERPLFEKINKADKNEKELLMSYTGSRIVGGDEA 380

  Fly   130 NPHCFPYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCV------------DMAKRALVFLGANE 182
            .....|:||.:..:.|:.|. ||.|||||:.::|||||:            |:    :|.||.:.
Zfish   381 EVASAPWQVMLYKRSPQELL-CGASLISDEWILTAAHCILYPPWNKNFTINDI----IVRLGKHS 440

  Fly   183 IKNAKEKGQVRLMVPSENFQIYPTWNPK-RLKDDIAIVRLPHAVSFNERIHPIQLP----KRHYE 242
             :...|:| :..:|..:...::|.:|.| .|..|||::.:...|.|...|||:.||    .::..
Zfish   441 -RTKYERG-IEKIVAIDEIIVHPKYNWKENLNRDIALLHMKKPVVFTSEIHPVCLPTKSIAKNLM 503

  Fly   243 YRSFKNKLAIASGWGR----YATGVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSGRNA 303
            :..:|.::   :|||.    :.:....:..||:.:.|.|:|...|:::..:.......|...:..
Zfish   504 FAGYKGRV---TGWGNLRESWTSNPTNLPTVLQQIHLPIVDQSICRNSTSVIITDNMFCAGYQPD 565

  Fly   304 RS----TCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDR-GYPAAFTKVASYLDWI 357
            .|    .|.||||||.|::.....:...:||.|:|.  |||| |....:|.:.....|:
Zfish   566 DSKRGDACEGDSGGPFVMKSPSDNRWYQIGIVSWGE--GCDRDGKYGFYTHLFRMRRWM 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	73/260 (28%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	73/261 (28%)
f2	XP_005169022.1	GLA	39..100	CDD:214503
		KR	126..206	CDD:214527
		KR	228..309	CDD:214527
		Thrombin_light	326..373	CDD:286482	10/49 (20%)
		Tryp_SPc	373..621	CDD:214473	73/259 (28%)
		Tryp_SPc	374..625	CDD:238113	73/261 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910