Protein Alignment CG6592 and HGF

DIOPT Version :10

• Sequence 1: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_000592.3
• Gene: HGF / 3082
• HGNCID: 4893
• Length: 728
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 74/292 - (25%)
• Similarity: 120/292 - (41%)
• Gaps: 72/292 - (24%)

  Fly    93 EDDREPLVLNLETTPLME----KMLPEGAMAMDRIFGG-----DVGNPHCFPYQVGMLLQRPKGL 148
            |.|..|.::||: .|::.    |.|        |:..|     ::|         .|:..|.:..
Human   470 EGDTTPTIVNLD-HPVISCAKTKQL--------RVVNGIPTRTNIG---------WMVSLRYRNK 516

  Fly   149 YWCGGSLISDKHVITAAHCV---DMAKRALVFLGANEI-----KNAKEKGQVRLMVPSENFQIYP 205
            :.||||||.:..|:||..|.   |: |....:||.:::     :..|:...|..:|
Human   517 HICGGSLIKESWVLTARQCFPSRDL-KDYEAWLGIHDVHGRGDEKCKQVLNVSQLV--------- 571

  Fly   206 TWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYATGVHAISNVL 270
             :.|:  ..|:.:::|......::.:..|.||  :|.....:.......|||  .||:.....:|
Human   572 -YGPE--GSDLVLMKLARPAVLDDFVSTIDLP--NYGCTIPEKTSCSVYGWG--YTGLINYDGLL 629

  Fly   271 RYVQLQIIDGRTCKSNFPLSYRG------TNICTSGRNARS-TCNGDSGGPLVLQRRHSKKRVLV 328
            |...|.|:....|..:    :||      :.||.......| .|.||.|||||.::.  |.|:::
Human   630 RVAHLYIMGNEKCSQH----HRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQH--KMRMVL 688

  Fly   329 GITSFGSIYGC---DRGYPAAFTKVASYLDWI 357
            |:...|.  ||   :|  |..|.:||.|..||
Human   689 GVIVPGR--GCAIPNR--PGIFVRVAYYAKWI 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	65/258 (25%)
HGF	NP_000592.3	PAN_APPLE	39..122	CDD:238074
		KR	126..208	CDD:214527
		KR	210..290	CDD:214527
		KR	304..384	CDD:214527
		KR	388..470	CDD:238056	74/292 (25%)
		Tryp_SPc	494..716	CDD:214473	64/257 (25%)